CAJ | 학술논문

1例36岁男性慢性乙型肝炎患者服用阿德福韦10 mg,1次/d.约6个月后,因抗病毒效果不佳改用恩替卡韦0.5 mg,1次/d.5个月后,加用阿德福韦10 mg,1次/d.联合用药5个月后,患者出现右侧跖趾关节麻木,肌酸激酶800 U/L.停用恩替卡韦第4天,肌酸激酶257 U/L,右侧跖趾关节麻木症状好转.
1례36세남성만성을형간염환자복용아덕복위10 mg,1차/d.약6개월후,인항병독효과불가개용은체잡위0.5 mg,1차/d.5개월후,가용아덕복위10 mg,1차/d.연합용약5개월후,환자출현우측척지관절마목,기산격매800 U/L.정용은체잡위제4천,기산격매257 U/L,우측척지관절마목증상호전.
A 36-year-old male patient with chronic hepatitis B received oral adefovir 10 mg once daily.About 6 months later,the treatment was switched to entecavir 0.5 mg once daily due to poor efficacy.Five months later,adefovir 10 mg once daily was added to his regimen.After 5 months of combination therapy,the patient developed a feeling of numbness on the right metatarsophalangeal joints.His creatine kinase level was 800 U/L.On the fourth day after entecavir withdrawal,his creatine kinase was 257 U/L,and the symptom of right metatarsophalangeal joints numbness was improved.