CAJ | 학술논문

1例61岁男性急性淋巴细胞白血病患者行化疗药物鞘内注射,因医生配药时拿错药物,误将5％碳酸氢钠注射液用作化疗药物溶媒.鞘内注射完毕后患者即出现下肢麻木,继之出现寒战、高热(体温最高40.1℃)、大汗、血压升高(190～210/106～110 mm Hg,1 mm Hg=0.133 kPa)、心率增快(170～ 180次/min)、尿潴留.给予甲泼尼龙、甘露醇静脉滴注,同时给予补液及导尿等处理.4h后患者体温、血压、心率恢复正常,6h后下肢麻木消失,12 h后可自行排尿.随访1周,患者未再出现类似症状.
1례61세남성급성림파세포백혈병환자행화료약물초내주사,인의생배약시나착약물,오장5％탄산경납주사액용작화료약물용매.초내주사완필후환자즉출현하지마목,계지출현한전、고열(체온최고40.1℃)、대한、혈압승고(190～210/106～110 mm Hg,1 mm Hg=0.133 kPa)、심솔증쾌(170～ 180차/min)、뇨저류.급여갑발니룡、감로순정맥적주,동시급여보액급도뇨등처리.4h후환자체온、혈압、심솔회복정상,6h후하지마목소실,12 h후가자행배뇨.수방1주,환자미재출현유사증상.
A 61-year-old male patient with acute lymphoblastic leukemia received intrathecal injection of chemotherapy drugs.A doctor in charge took mistakenly the 5％ sodium bicarbonate injection as solvent.After intrathecal injection,the patient presented lower limbs numbness,followed by chills,fever (peak temperature 40.1 ℃),sweating,elevated blood pressure (190-210/106-110 mm Hg),increased heart rate (170-180 beats/min),and urinary retention.The patient was given an Ⅳ infusion of methylprednisolone and mannitol,and at the same time,fluid supplement and urethral catheterization were given.The patient's temperature,blood pressure,and heart rate returned to normal 4 hours later,numbness of lower limbs disappeared 6 hours later,and urinated on himself 12 hours later.There was no similar symptoms recurrence at one-week follow up.