药物不良反应杂志
藥物不良反應雜誌
약물불량반응잡지
ADVERSE DRUG REACTIONS JOURNAL
2014年
1期
39-40
,共2页
华法林%安乃近%臀%血肿
華法林%安迺近%臀%血腫
화법림%안내근%둔%혈종
Warfarin%Dipyrone%Buttock%Hematoma
1例心脏瓣膜置换术后一直口服华法林(2.5 mg,1次/d,已5年)的51岁男性患者因感冒肌内注射安乃近(剂量不详),第3天出现左臀部肿痛、皮下瘀斑.超声检查示左臀部皮下低回声区.实验室检查:国际标准化比值(INR) 6.2.停用华法林,静脉滴注维生素K1 40 mg,1次/d.3d后,INR降至1.0,行左臀切开引流术.术后第2天INR l.2,恢复原剂量华法林口服.2周后,瘀斑面积减小,INR 2.0.术后6周瘀斑完全消退,INR 2.1.
1例心髒瓣膜置換術後一直口服華法林(2.5 mg,1次/d,已5年)的51歲男性患者因感冒肌內註射安迺近(劑量不詳),第3天齣現左臀部腫痛、皮下瘀斑.超聲檢查示左臀部皮下低迴聲區.實驗室檢查:國際標準化比值(INR) 6.2.停用華法林,靜脈滴註維生素K1 40 mg,1次/d.3d後,INR降至1.0,行左臀切開引流術.術後第2天INR l.2,恢複原劑量華法林口服.2週後,瘀斑麵積減小,INR 2.0.術後6週瘀斑完全消退,INR 2.1.
1례심장판막치환술후일직구복화법림(2.5 mg,1차/d,이5년)적51세남성환자인감모기내주사안내근(제량불상),제3천출현좌둔부종통、피하어반.초성검사시좌둔부피하저회성구.실험실검사:국제표준화비치(INR) 6.2.정용화법림,정맥적주유생소K1 40 mg,1차/d.3d후,INR강지1.0,행좌둔절개인류술.술후제2천INR l.2,회복원제량화법림구복.2주후,어반면적감소,INR 2.0.술후6주어반완전소퇴,INR 2.1.
A 51-year-old male patient,who was treated with warfarin 2.5 mg once daily for 5 years after cardiac valve replacement,received IM dipyrone for his cold (dose not stated).He developed pain,swelling and ecchymosis of left buttock after 3 days.Ultrasonic examination showed low echo area on the left buttock.Laboratory tests showed an international normalized ratio (INR) 6.2.Warfarin was stopped and an ⅣV infusion of vitamin K1 40 mg once daily was given.Three days later,the INR value decreased to 1.0.Incision and drainage on the left buttock was performed.On the second day after operation,the INR was 1.2and warfarin was received again according to original dosage.Two weeks later,the area of ecchymosis was reduced,and INR level was 2.0.After one month of follow-up,the ecchymosis subsided completely,the INR level was 2.1.