CAJ | 학술논문

1例13岁男性急性淋巴细胞白血病异基因移植术后患儿因肺部感染静脉滴注阿奇霉素20.8 mg/kg(患儿体重24 kg).首次静脉滴注阿奇霉素即将结束时,患儿出现心悸,心率225次/min,血压75/45 mmHg(l mmHg =0.133 kPa),脉搏血氧饱和度0.98;心电图提示室上性心动过速,QRS波变窄;床边心脏超声检查示心包少量积液,左心室后壁运动稍减弱,射血分数0.58.立即停用阿奇霉素,交替压迫患儿颈动脉窦和眼球,约10 min后患儿心率降至120次/min,心率为窦性,血压92/62 mmHg.2d后心电图正常,心率87次/min.
1례13세남성급성림파세포백혈병이기인이식술후환인인폐부감염정맥적주아기매소20.8 mg/kg(환인체중24 kg).수차정맥적주아기매소즉장결속시,환인출현심계,심솔225차/min,혈압75/45 mmHg(l mmHg =0.133 kPa),맥박혈양포화도0.98;심전도제시실상성심동과속,QRS파변착;상변심장초성검사시심포소량적액,좌심실후벽운동초감약,사혈분수0.58.립즉정용아기매소,교체압박환인경동맥두화안구,약10 min후환인심솔강지120차/min,심솔위두성,혈압92/62 mmHg.2d후심전도정상,심솔87차/min.
A 13-year-old boy (weighing 24 kg) after allogeneic transplantation due to acute lymphoblastic leukemia received an Ⅳ infusion of azithromycin at a dose of 20.8 mg/kg because of pneumonia.At the end of intravenous infusion of azithromycin for the first time,the boy developed palpitation and the heart rate was 225 beats/min,blood pressure 75/45 mmHg,and oxygen saturation 0.98.The ECG examination showed supraventricular tachycardia and narrow QRS complex.The bedside echocardiographic examination showed a small amount of pericardial effusion,slight decrease of the motion range of left ventricular posterior wall,and ejection fraction 0.58.Azithromycin was discontinued immediately and his carotid sinus and eyeball were pressed alternately.About 10 minutes later,his heart rate dropped to 120 beats/min,sinus rhythm recovered,and blood pressure was 92/62 mmHg.Two days later,his ECG examination showed normal and his heart rate was 87 beats/min.