中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2012年
12期
933-936
,共4页
青光眼,新生血管性%手术%曲安奈德%玻璃体腔注射%小梁切除术,复合式
青光眼,新生血管性%手術%麯安奈德%玻璃體腔註射%小樑切除術,複閤式
청광안,신생혈관성%수술%곡안내덕%파리체강주사%소량절제술,복합식
Glaucoma,neovascular%Surgery%Triamcinolone acetonide%Intravitreal injection%Trabeculectomy,compound
目的 探讨玻璃体腔注射曲安奈德后行复合式小梁切除术对新生血管性青光眼的治疗效果.方法 新生血管性青光眼51例(51眼).随机分为两组,试验组26例,对照组25例.试验组先在局麻下玻璃体腔注射曲安奈德4 mg,待虹膜新生血管消退后再行复合式小梁切除术.对照组行常规复合式小梁切除术.术后随访6 ～ 24个月,观察玻璃体腔注射曲安奈德后虹膜及前房角新生血管消退时间,注药后眼压、晶状体改变,以及复合式小梁切除术后眼压、前房、视力、滤过泡、前房积血、前房渗出情况.结果 玻璃体腔注药后26眼4～10 d虹膜新生血管完全消退.复合式小梁切除术后两组眼压、前房、滤过泡差异有统计学意义(P＜0.05)；两组术后视力差异无统计学意义(P＞0.05).结论 玻璃体内注射曲安奈德后再行复合式小梁切除术能有效治疗新生血管性青光眼,可以使虹膜新生血管快速消退或萎缩,降低术后前房积血的发生率、提高手术成功率.
目的 探討玻璃體腔註射麯安奈德後行複閤式小樑切除術對新生血管性青光眼的治療效果.方法 新生血管性青光眼51例(51眼).隨機分為兩組,試驗組26例,對照組25例.試驗組先在跼痳下玻璃體腔註射麯安奈德4 mg,待虹膜新生血管消退後再行複閤式小樑切除術.對照組行常規複閤式小樑切除術.術後隨訪6 ～ 24箇月,觀察玻璃體腔註射麯安奈德後虹膜及前房角新生血管消退時間,註藥後眼壓、晶狀體改變,以及複閤式小樑切除術後眼壓、前房、視力、濾過泡、前房積血、前房滲齣情況.結果 玻璃體腔註藥後26眼4～10 d虹膜新生血管完全消退.複閤式小樑切除術後兩組眼壓、前房、濾過泡差異有統計學意義(P＜0.05)；兩組術後視力差異無統計學意義(P＞0.05).結論 玻璃體內註射麯安奈德後再行複閤式小樑切除術能有效治療新生血管性青光眼,可以使虹膜新生血管快速消退或萎縮,降低術後前房積血的髮生率、提高手術成功率.
목적 탐토파리체강주사곡안내덕후행복합식소량절제술대신생혈관성청광안적치료효과.방법 신생혈관성청광안51례(51안).수궤분위량조,시험조26례,대조조25례.시험조선재국마하파리체강주사곡안내덕4 mg,대홍막신생혈관소퇴후재행복합식소량절제술.대조조행상규복합식소량절제술.술후수방6 ～ 24개월,관찰파리체강주사곡안내덕후홍막급전방각신생혈관소퇴시간,주약후안압、정상체개변,이급복합식소량절제술후안압、전방、시력、려과포、전방적혈、전방삼출정황.결과 파리체강주약후26안4～10 d홍막신생혈관완전소퇴.복합식소량절제술후량조안압、전방、려과포차이유통계학의의(P＜0.05)；량조술후시력차이무통계학의의(P＞0.05).결론 파리체내주사곡안내덕후재행복합식소량절제술능유효치료신생혈관성청광안,가이사홍막신생혈관쾌속소퇴혹위축,강저술후전방적혈적발생솔、제고수술성공솔.
Objective To investigate the therapeutic effect of intravitreal triamcinolone acetonide combined with compound trabculectomy for treatment of neovascular glaucoma.Methods 51 patients (51 eyes) with neovascular glaucoma in our hospital were treated.The patients were randomly divided into two groups:experimentmal group 26 eyes,and control group 25 eyes.Patients in experimentmal group was injected with triamcinolone 4 mg in vitreous cavity before the compound trabeculectomy operation under the local anesthesia.After new blood vessels of iris regressed,we carried out the combined trabeculectomy operation.The patients of control Group only received the compound trabeculectomy.All patients received follow up from 6 months to 24 months.We observed the phase of new blood vessels in iris and anterior chamber after intravitreal triamcinolone acetonide,intraocular pressure,crystal changes after injection,intraocular pressure,shallow anterior chamber,anterior chamber bleeding,the anterior chamber inflammation,filtrating bleb and vision after compound trabeculectomy operation.Results In 26 patients in group A,whose new blood vessels in iris completely regressed in 4 ～ 10 days.The intraocular pressure,anterior chamber and filtrating blebs had statistical significance between the two groups(P ＜ 0.05).There was no statistically significant in vision.(P ＞ 0.05).Conclusion Intravitreal injection of triamcinolone acetonide combined with trabeculectomy surgery can effectively treat neovascular glaucoma,and iris neovascularizations quickly fade or shrink.It can reduce the incidence of postoperative bleeding in the anterior chamber and improve the success rate of operation effectively.
