中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2014年
4期
294-297
,共4页
张斯%付琦%康鑫鑫%王元
張斯%付琦%康鑫鑫%王元
장사%부기%강흠흠%왕원
右美托咪定%手术,眼科%麻醉,静脉%躁动,苏醒期
右美託咪定%手術,眼科%痳醉,靜脈%躁動,囌醒期
우미탁미정%수술,안과%마취,정맥%조동,소성기
Dexmedetomidine%Surgery,ophthalmic,pediatric%Anesthesia,intravenous%Agitation,emergence
目的 探讨右美托咪定用于小儿眼科手术以预防静脉麻醉苏醒期躁动的效果及安全性.方法 小儿眼外伤手术60例.随机分为两组:右美托咪定组(A组)和对照组(B组),每组30例.A组:0.5 μg/kg的右美托咪定用生理盐水稀释至20 m1,于麻醉诱导前用微量泵10 min内注射完毕,B组:于相同时间注射等量生理盐水.观察两组注射前(T0)、注射后5 min(T1)、清醒时(T2)、拔管后5 min(T3)、拔管后10 min(T4)的平均动脉压、心率、脉搏血氧饱和度,及全麻苏醒期躁动评分和躁动率之间的差异.结果 两组患儿性别、年龄、体重、手术时间及各时间点血氧饱和度比较差异无统计学意义(x2=0.082,t=0.398,0.296,0.765,P＞0.05);与B组相比,A组T1时的HR,T2、T3及T4时的平均动脉压、心率及烦躁发生率均有明显的降低,差异有统计学意义(t=5.651,12.438,10.928,14.247,13.819,17.717,15.141,2.321,8.797,8.797,x2=5.963,8.365,6.667,P＜0.05).结论 麻醉诱导前10 min内静脉输注0.5 μg/kg右美托咪定,可安全有效地降低眼科手术患儿全麻苏醒期躁动的发生.
目的 探討右美託咪定用于小兒眼科手術以預防靜脈痳醉囌醒期躁動的效果及安全性.方法 小兒眼外傷手術60例.隨機分為兩組:右美託咪定組(A組)和對照組(B組),每組30例.A組:0.5 μg/kg的右美託咪定用生理鹽水稀釋至20 m1,于痳醉誘導前用微量泵10 min內註射完畢,B組:于相同時間註射等量生理鹽水.觀察兩組註射前(T0)、註射後5 min(T1)、清醒時(T2)、拔管後5 min(T3)、拔管後10 min(T4)的平均動脈壓、心率、脈搏血氧飽和度,及全痳囌醒期躁動評分和躁動率之間的差異.結果 兩組患兒性彆、年齡、體重、手術時間及各時間點血氧飽和度比較差異無統計學意義(x2=0.082,t=0.398,0.296,0.765,P＞0.05);與B組相比,A組T1時的HR,T2、T3及T4時的平均動脈壓、心率及煩躁髮生率均有明顯的降低,差異有統計學意義(t=5.651,12.438,10.928,14.247,13.819,17.717,15.141,2.321,8.797,8.797,x2=5.963,8.365,6.667,P＜0.05).結論 痳醉誘導前10 min內靜脈輸註0.5 μg/kg右美託咪定,可安全有效地降低眼科手術患兒全痳囌醒期躁動的髮生.
목적 탐토우미탁미정용우소인안과수술이예방정맥마취소성기조동적효과급안전성.방법 소인안외상수술60례.수궤분위량조:우미탁미정조(A조)화대조조(B조),매조30례.A조:0.5 μg/kg적우미탁미정용생리염수희석지20 m1,우마취유도전용미량빙10 min내주사완필,B조:우상동시간주사등량생리염수.관찰량조주사전(T0)、주사후5 min(T1)、청성시(T2)、발관후5 min(T3)、발관후10 min(T4)적평균동맥압、심솔、맥박혈양포화도,급전마소성기조동평분화조동솔지간적차이.결과 량조환인성별、년령、체중、수술시간급각시간점혈양포화도비교차이무통계학의의(x2=0.082,t=0.398,0.296,0.765,P＞0.05);여B조상비,A조T1시적HR,T2、T3급T4시적평균동맥압、심솔급번조발생솔균유명현적강저,차이유통계학의의(t=5.651,12.438,10.928,14.247,13.819,17.717,15.141,2.321,8.797,8.797,x2=5.963,8.365,6.667,P＜0.05).결론 마취유도전10 min내정맥수주0.5 μg/kg우미탁미정,가안전유효지강저안과수술환인전마소성기조동적발생.
Objective To investigate the security and effectiveness of dexmedetomidine infusion for prevention of emergence agitation from intravenous anesthesia in ophthahmic surgery.Methods 60 operations of pediatric ocular trauma were randomly divided into two groups:The dexmedetomidine group (group A,n =30) and the control group(group B,n =30)).When anesthesia induction was administrated,normal saline 20 ml or dexmedetomidine 0.5 μg/kg diluted to 20 ml was intravenously infused in 10 minutes.The difference between the mean artery pressure(MAP),heart rate(HR) and SpO2 before injection(T0),5 minutes after injection(T1),awakening(T2),5 minutes after extubation(T3),10 minutes after extubation (T4) and the agitation scale were observed in two groups.Results There was no significant difference between the two groups in sex,age,weight,time of operation and SpO2 in T0 to T4 (x2 =0.082,t =0.398,0.296,0.765,P ＞0.05).Compared with group B,the HR of T1,the MAP,HR and agitation scale of T2,T3 and T4 were lower in group A (t =5.651,12.438,10.928,14.247,13.819,17.717,15.141,2.321,8.797,8.797,x2 =5.963,8.365,6.667,P ＜ 0.05) in two groups.Conclusion Dexmedetomidine of 0.5 μg/kg was intravenously infused 10 min before anesthesia induction can safely and effectively reduce the occurrence of emergence agitation from anesthesia in pediatric ophthalmic surgery.
