中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2014年
5期
350-354
,共5页
范军华%何伟杰%叶瑞珍%李学喜
範軍華%何偉傑%葉瑞珍%李學喜
범군화%하위걸%협서진%리학희
角膜穿孔%羊膜卷%填塞%C3F8气体,前房填充%内皮细胞,角膜
角膜穿孔%羊膜捲%填塞%C3F8氣體,前房填充%內皮細胞,角膜
각막천공%양막권%전새%C3F8기체,전방전충%내피세포,각막
Perforation,corneal%Roll,amniotic%Plugging%Gas C3F8,tamponade,anterior chamber%Cell,endothelial,corneal
目的 观察羊膜卷填塞联合C3F8气体填充治疗角膜穿孔术后羊膜的演变及其对角膜内皮细胞的影响.方法 因各种原因所致角膜穿孔而施行羊膜卷填塞联合前房C3F8气体填充术共56例(56眼).术中以20％C3F8气体填充前房.术后观察前房深度、房水渗漏情况、气泡维持时间、角膜内皮细胞密度及形态,以及羊膜卷与角膜融合情况.结果 56例角膜穿孔均得到修复,羊膜卷无脱落,术后2个月时羊膜卷与角膜逐渐融合,其间无明显缝隙,C3F8气体在前房存留时间5～16 d,平均(8.2±4.8)d.术前与术后1个月、2个月时角膜内皮细胞密度差异均无统计学意义(=1.02,1.71,P ＞0.05),六角形细胞比例术后1个月时低于术前(t=2.13,P＜0.05),术后1个月与术后2个月时差异无统计学意义(t=1.65,P＞0.05).结论 羊膜卷填塞联合前房C3F8气体填充可有效修复角膜穿孔,术后羊膜卷与角膜融合好,C3F8气体能较长时间维持前房深度,防止房水渗漏,对角膜内皮细胞影响甚小.
目的 觀察羊膜捲填塞聯閤C3F8氣體填充治療角膜穿孔術後羊膜的縯變及其對角膜內皮細胞的影響.方法 因各種原因所緻角膜穿孔而施行羊膜捲填塞聯閤前房C3F8氣體填充術共56例(56眼).術中以20％C3F8氣體填充前房.術後觀察前房深度、房水滲漏情況、氣泡維持時間、角膜內皮細胞密度及形態,以及羊膜捲與角膜融閤情況.結果 56例角膜穿孔均得到脩複,羊膜捲無脫落,術後2箇月時羊膜捲與角膜逐漸融閤,其間無明顯縫隙,C3F8氣體在前房存留時間5～16 d,平均(8.2±4.8)d.術前與術後1箇月、2箇月時角膜內皮細胞密度差異均無統計學意義(=1.02,1.71,P ＞0.05),六角形細胞比例術後1箇月時低于術前(t=2.13,P＜0.05),術後1箇月與術後2箇月時差異無統計學意義(t=1.65,P＞0.05).結論 羊膜捲填塞聯閤前房C3F8氣體填充可有效脩複角膜穿孔,術後羊膜捲與角膜融閤好,C3F8氣體能較長時間維持前房深度,防止房水滲漏,對角膜內皮細胞影響甚小.
목적 관찰양막권전새연합C3F8기체전충치료각막천공술후양막적연변급기대각막내피세포적영향.방법 인각충원인소치각막천공이시행양막권전새연합전방C3F8기체전충술공56례(56안).술중이20％C3F8기체전충전방.술후관찰전방심도、방수삼루정황、기포유지시간、각막내피세포밀도급형태,이급양막권여각막융합정황.결과 56례각막천공균득도수복,양막권무탈락,술후2개월시양막권여각막축점융합,기간무명현봉극,C3F8기체재전방존류시간5～16 d,평균(8.2±4.8)d.술전여술후1개월、2개월시각막내피세포밀도차이균무통계학의의(=1.02,1.71,P ＞0.05),륙각형세포비례술후1개월시저우술전(t=2.13,P＜0.05),술후1개월여술후2개월시차이무통계학의의(t=1.65,P＞0.05).결론 양막권전새연합전방C3F8기체전충가유효수복각막천공,술후양막권여각막융합호,C3F8기체능교장시간유지전방심도,방지방수삼루,대각막내피세포영향심소.
Objective To observe the evolution of amnion and influnce on corneal endothelium in amniotic roll plugging combined with C3F8 tamponade in anterior chamber to treat corneal perforation.Methods 56 eyes of 56 patients with corneal perforation accepted the operation of amniotic roll plugging combined with C3F8 tamponade in anterior chamber and the concentration of C3F8 gas was 20％.Anterior chamber depth,aqueous leakage,bubbles maintenance time,corneal endothelial cell density and morphology and the fusion of amniotic roll and corneal tissue were observed.Results Corneal perforation of 56 eyes were all repaired without amniotic roll falling off.The fusion of amniotic roll and corneal tissue was observed at 2 months after operation,and the amniotic roll and corneal tissue fused well and no gap was examined.The C3F8 gas stayed in the anterior chamber for 5 ～ 16 days,average of (8.2 ± 4.8) days.There was no significant difference in corneal endothelial cell density between preoperative and postoperative 1 month or 2 month.The percentage of hexagonal cells decreased at postoperative 1 month compared with preoperative (t =2.13,P ＞ 0.05),and there was no significant difference between postoperative 1 month and 2 months (t =1.65,P ＞ 0.05).Conclusion Amniotic roll plugging combined with C3 F8 gas tamponade in anterior chamber can effectively repair corneal perforation,and the amniotic roll and cornea can fuse well after operation.C3F8 gas can stay in the anterior chamber long enough to maintain the anterior chamber depth and prevent leakage of aqueous humor.Little influnce on the corneal endothelium was observed.
