中华胰腺病杂志
中華胰腺病雜誌
중화이선병잡지
CHINESE JOURNAL OF PANCREATOLOGY
2013年
3期
170-174
,共5页
张捷%吴敏%冯文焕%邵琳琳
張捷%吳敏%馮文煥%邵琳琳
장첩%오민%풍문환%소림림
胰腺%超声%脂肪肝%糖尿病,2型%葡萄糖代谢障碍
胰腺%超聲%脂肪肝%糖尿病,2型%葡萄糖代謝障礙
이선%초성%지방간%당뇨병,2형%포도당대사장애
Pancreas%Ultrasound%Fatty liver%Diabetes mellitus,type 2%Glucose metabolism disorders
目的 研究糖代谢异常包括2型糖尿病患者的胰腺大小及回声的特征,并探讨其影响因素.方法 收集南京鼓楼医院糖代谢正常、糖调节受损、新诊断2型糖尿病及已诊断2型糖尿病患者157例.用直方图方法定量测量肝、肾、胰腺感兴趣区平均灰阶强度,并计算肝肾回声比值、肝脏衰减系数,根据公式推算肝脏脂肪含量.超声测量胰腺头、体、尾部大小,三者相加作为胰腺大小指标.将胰腺大小、回声强度进行单因素和多因素回归分析.结果 胰腺大小为2.39～6.09 cm,平均(4.43±0.59) cm,≤5 cm的130例,＞5 cm的27例.胰腺回声41.0～190.6,平均回声120.0±31.1,≤120的83例,＞120的74例.肝脂肪含量-1.11％ ～62.50％,平均(15.67±11.97)％.单因素分析显示,胰腺大小与年龄大小、肥胖程度相关；胰腺回声强度与肥胖程度、入组受试者类型、血糖控制水平、脂肪肝严重程度分级相关(P值均＜0.05).多因素分析显示肥胖程度是预测胰腺大小和回声强度最重要的影响因素(P值均＜0.05).结论 超声定量测量胰腺大小和回声可以反映胰腺脂肪浸润的程度,有一定的临床应用价值.
目的 研究糖代謝異常包括2型糖尿病患者的胰腺大小及迴聲的特徵,併探討其影響因素.方法 收集南京鼓樓醫院糖代謝正常、糖調節受損、新診斷2型糖尿病及已診斷2型糖尿病患者157例.用直方圖方法定量測量肝、腎、胰腺感興趣區平均灰階彊度,併計算肝腎迴聲比值、肝髒衰減繫數,根據公式推算肝髒脂肪含量.超聲測量胰腺頭、體、尾部大小,三者相加作為胰腺大小指標.將胰腺大小、迴聲彊度進行單因素和多因素迴歸分析.結果 胰腺大小為2.39～6.09 cm,平均(4.43±0.59) cm,≤5 cm的130例,＞5 cm的27例.胰腺迴聲41.0～190.6,平均迴聲120.0±31.1,≤120的83例,＞120的74例.肝脂肪含量-1.11％ ～62.50％,平均(15.67±11.97)％.單因素分析顯示,胰腺大小與年齡大小、肥胖程度相關；胰腺迴聲彊度與肥胖程度、入組受試者類型、血糖控製水平、脂肪肝嚴重程度分級相關(P值均＜0.05).多因素分析顯示肥胖程度是預測胰腺大小和迴聲彊度最重要的影響因素(P值均＜0.05).結論 超聲定量測量胰腺大小和迴聲可以反映胰腺脂肪浸潤的程度,有一定的臨床應用價值.
목적 연구당대사이상포괄2형당뇨병환자적이선대소급회성적특정,병탐토기영향인소.방법 수집남경고루의원당대사정상、당조절수손、신진단2형당뇨병급이진단2형당뇨병환자157례.용직방도방법정량측량간、신、이선감흥취구평균회계강도,병계산간신회성비치、간장쇠감계수,근거공식추산간장지방함량.초성측량이선두、체、미부대소,삼자상가작위이선대소지표.장이선대소、회성강도진행단인소화다인소회귀분석.결과 이선대소위2.39～6.09 cm,평균(4.43±0.59) cm,≤5 cm적130례,＞5 cm적27례.이선회성41.0～190.6,평균회성120.0±31.1,≤120적83례,＞120적74례.간지방함량-1.11％ ～62.50％,평균(15.67±11.97)％.단인소분석현시,이선대소여년령대소、비반정도상관；이선회성강도여비반정도、입조수시자류형、혈당공제수평、지방간엄중정도분급상관(P치균＜0.05).다인소분석현시비반정도시예측이선대소화회성강도최중요적영향인소(P치균＜0.05).결론 초성정량측량이선대소화회성가이반영이선지방침윤적정도,유일정적림상응용개치.
Objective To investigate the pancreas size and echo characteristics of patients with glucose metabolism disorders including type 2 diabetes,and to study its related factors.Methods One hundred and fifty-seven patients from Nanjing Drum Tower Hospital with normal glucose metabolism,impaired glucose regulation,newly diagnosed type 2 diabetes and established type 2 diabetes were collected.The average gray scale intensity of the liver,kidney,pancreas region of interest was measured by using the histogram method.Then the liver and kidney echo ratio,liver attenuation coefficient was calculated,and the fat content of liver was determined by using formula.The size of pancreas head,body and tail was detected by ultrasound,and the sum of three values was used as the pancreas size indicator.Univariate and multivariate logistic regression analysis was performed on the size of pancreas and intensity of echo.Results The size of pancreas ranged from 2.39 ～ 6.09 cm with a mean size of (4.43 ± 0.59) cm,and the size was ≤ 5 cm in 130patients,＞5 cmin 27 patients.The intensity of echo ranged from 41.0 ～ 190.6 with a mean number of 120.0 ±31.1,and the intensity of echo was ≤120 in 83 patients,＞ 120 in 74 patients.The content of liver fat ranged from-1.11％ ～ 62.50％ with a mean number of (15.67± 11.97)％.Univariate logistic regression analysis suggested the size of pancreas was related to age and obesity,and pancreas echo was related to obesity degree,types of participants,the level of blood glucose,and grade of fatty liver (all P ＜ 0.05).Multivariate logistic regression analysis indicated obesity degree is the most important factor for prediction of pancreas size and echo (P ＜ 0.05).Conclusions Quantitative ultrasound measurement of pancreas size and echo can reflect the degree of fat infiltration of pancreas,and it has some clinical value.
