中国地方病学杂志
中國地方病學雜誌
중국지방병학잡지
CHINESE JOURNAL OF ENDEMIOLOGY
2009年
6期
658-661
,共4页
大骨节病%硒%儿童%成人%流行病学监测%结果评价
大骨節病%硒%兒童%成人%流行病學鑑測%結果評價
대골절병%서%인동%성인%류행병학감측%결과평개
Kaschin-Beck disease%Selenium%Children%Adults%Epidemiological monitoring%Outcome assessment
目的 掌握陕西省儿童及成人大骨节病病情现状,评估防治效果,为防治决策提供科学依据.方法 根据大骨节病历史资料,2008年在陕西省选择8个市10个病区县的10个重病村,对全部7～12岁儿童进行临床检查,拍摄右手X线片;选择10个市37个病区县的65个重病村,对≥16岁人群进行临床检查;在旬邑县的东、南、西、北4个方向各选择1个病区村补硒,在项目实施前、项目干预6个月,每个病区村检测30户家庭的硒碘盐含硒量,每村对30名7～12岁儿童检测发硒.结果 共对862名儿童进行临床检查,未检出Ⅰ度以上病例.X线检查862人,检出1例干骺端阳性病例,检出率为0.12%(1/862);65个病区村16岁以上成人共有35 638名,检查30 599人,受检率为85.86%(30 599/35 638).共检出大骨节病病例5108例,总检出率为16.69%(5108/30 599),其中I度检出率为9.73%(2977/30 599),Ⅱ度检出率为5.40%(1652/30 599),Ⅲ度检出率为1.57%(479/30 599),36～60岁患者占患者总数的65.7%(3355/5108).旬邑县在项目实施前、项目干预6个月,硒碘盐含硒量分别为(5.43±3.19)、(7.74±1.81)mg/kg,儿童头发含硒量分别为(0.3933±0.0930)、(0.3613±0.0997)mg/kg.结论 陕西省儿童大骨节病病情稳定下降,成人大骨节病病情严峻,应积极开展成人大骨节病治疗工作,并加大健康教育宣传力度,巩固防治成果.
目的 掌握陝西省兒童及成人大骨節病病情現狀,評估防治效果,為防治決策提供科學依據.方法 根據大骨節病歷史資料,2008年在陝西省選擇8箇市10箇病區縣的10箇重病村,對全部7～12歲兒童進行臨床檢查,拍攝右手X線片;選擇10箇市37箇病區縣的65箇重病村,對≥16歲人群進行臨床檢查;在旬邑縣的東、南、西、北4箇方嚮各選擇1箇病區村補硒,在項目實施前、項目榦預6箇月,每箇病區村檢測30戶傢庭的硒碘鹽含硒量,每村對30名7～12歲兒童檢測髮硒.結果 共對862名兒童進行臨床檢查,未檢齣Ⅰ度以上病例.X線檢查862人,檢齣1例榦骺耑暘性病例,檢齣率為0.12%(1/862);65箇病區村16歲以上成人共有35 638名,檢查30 599人,受檢率為85.86%(30 599/35 638).共檢齣大骨節病病例5108例,總檢齣率為16.69%(5108/30 599),其中I度檢齣率為9.73%(2977/30 599),Ⅱ度檢齣率為5.40%(1652/30 599),Ⅲ度檢齣率為1.57%(479/30 599),36～60歲患者佔患者總數的65.7%(3355/5108).旬邑縣在項目實施前、項目榦預6箇月,硒碘鹽含硒量分彆為(5.43±3.19)、(7.74±1.81)mg/kg,兒童頭髮含硒量分彆為(0.3933±0.0930)、(0.3613±0.0997)mg/kg.結論 陝西省兒童大骨節病病情穩定下降,成人大骨節病病情嚴峻,應積極開展成人大骨節病治療工作,併加大健康教育宣傳力度,鞏固防治成果.
목적 장악합서성인동급성인대골절병병정현상,평고방치효과,위방치결책제공과학의거.방법 근거대골절병역사자료,2008년재합서성선택8개시10개병구현적10개중병촌,대전부7～12세인동진행림상검사,박섭우수X선편;선택10개시37개병구현적65개중병촌,대≥16세인군진행림상검사;재순읍현적동、남、서、북4개방향각선택1개병구촌보서,재항목실시전、항목간예6개월,매개병구촌검측30호가정적서전염함서량,매촌대30명7～12세인동검측발서.결과 공대862명인동진행림상검사,미검출Ⅰ도이상병례.X선검사862인,검출1례간후단양성병례,검출솔위0.12%(1/862);65개병구촌16세이상성인공유35 638명,검사30 599인,수검솔위85.86%(30 599/35 638).공검출대골절병병례5108례,총검출솔위16.69%(5108/30 599),기중I도검출솔위9.73%(2977/30 599),Ⅱ도검출솔위5.40%(1652/30 599),Ⅲ도검출솔위1.57%(479/30 599),36～60세환자점환자총수적65.7%(3355/5108).순읍현재항목실시전、항목간예6개월,서전염함서량분별위(5.43±3.19)、(7.74±1.81)mg/kg,인동두발함서량분별위(0.3933±0.0930)、(0.3613±0.0997)mg/kg.결론 합서성인동대골절병병정은정하강,성인대골절병병정엄준,응적겁개전성인대골절병치료공작,병가대건강교육선전력도,공고방치성과.
Objective To master the status of Kaschin-Beck disease(KBD) in children and adults, assess the effect of prevention, and provide scientific basis for control strategies. Methods Based on history data, children aged 7-12 years in 10 heavy KBD villages of 10 counties of 8 cities were clinically examined and the X-Ray of right hand examination was conducted. Clinical examinations were carried out in the people over 16 years in 65 heavy KBD villages of 37 counties of 10 cities. One village was respectively selected in four directions of Xunyi countyto supply selenium(Se). The content of Se in hair of the 30 children aged 7 - 12 years was detected before and six months after the supplement of Se in each village. And the content of Se in selenium-iodine salt was detected in 30 families of each village. Results Among the 862 children, no cases beyond 1 degree were detected in the clinical examination. One out of 862 children had pathological changes in metaphysis and the detectable rate of X-Ray was 0.21%(1/862). Total 30 599 people in 65 villages were examined, aceounting for 88.56%(30 599/ 35 638). The total detectable rate of KBD was 16.69%(5108/30 599), and the detectable rate of Ⅰ degree, Ⅱ degree, Ⅲ degree was 9.73% (2977/30 599),5.4%(1652/30 599), 1.57% (479/30 599), respectively. The patients aged 36～60 years accounted for 65.7%(3355/5108) of the total patients. The eontent of Se was (5.43±3.19) mg/kg and (7.74±1.81)mg/kg respectively in the period before and 6 months after the supplement, and the content of Se in hair of children was (0.3933±0.0930)mg/kg and (0.3613±0.0997)mg/kg, respectively. Conclusions KBD in children is in a steady decrease in Shanxi, but the situation of KBD in adults is serious. The treatment for the adult KBD patients should be carried out actively, and health education should be strengthened to consolidate the achievements of prevention and control of the KBD.
