中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
1期
56-58
,共3页
连续性肾替代治疗%肾功能衰竭%单核细胞%炎性反应
連續性腎替代治療%腎功能衰竭%單覈細胞%炎性反應
련속성신체대치료%신공능쇠갈%단핵세포%염성반응
Continuous renal replacement therapy%Acute renal failure%Monocyte%Inflammation response
目的 探讨连续性肾脏替代治疗(CRRT)对重症急性肾功能衰竭(ARF)患者单核细胞功能的影响.方法 动态检测42例接受CRRT的重症ARF患者单核细胞功能,并与健康人进行比较.结果 ARF患者单核细胞分泌细胞因子功能高于健康人群[TNF-α:(1 212.61±107.43)与(857.34±83.45) ng/L,IL-6:(2 518.22±228.22)与(1 948.13±218.23) ng/L,IL-8:(416.18±54.46)与(229.31 ±39.83) ng/L](t=6.47、7.09、6.45,均P＜0.05),CRRT治疗48 h后,单核细胞细胞分泌功能恢复至正常水平.结论 CRRT可降低ARF单核细胞的细胞因子分泌功能,下调全身炎性反应.
目的 探討連續性腎髒替代治療(CRRT)對重癥急性腎功能衰竭(ARF)患者單覈細胞功能的影響.方法 動態檢測42例接受CRRT的重癥ARF患者單覈細胞功能,併與健康人進行比較.結果 ARF患者單覈細胞分泌細胞因子功能高于健康人群[TNF-α:(1 212.61±107.43)與(857.34±83.45) ng/L,IL-6:(2 518.22±228.22)與(1 948.13±218.23) ng/L,IL-8:(416.18±54.46)與(229.31 ±39.83) ng/L](t=6.47、7.09、6.45,均P＜0.05),CRRT治療48 h後,單覈細胞細胞分泌功能恢複至正常水平.結論 CRRT可降低ARF單覈細胞的細胞因子分泌功能,下調全身炎性反應.
목적 탐토련속성신장체대치료(CRRT)대중증급성신공능쇠갈(ARF)환자단핵세포공능적영향.방법 동태검측42례접수CRRT적중증ARF환자단핵세포공능,병여건강인진행비교.결과 ARF환자단핵세포분비세포인자공능고우건강인군[TNF-α:(1 212.61±107.43)여(857.34±83.45) ng/L,IL-6:(2 518.22±228.22)여(1 948.13±218.23) ng/L,IL-8:(416.18±54.46)여(229.31 ±39.83) ng/L](t=6.47、7.09、6.45,균P＜0.05),CRRT치료48 h후,단핵세포세포분비공능회복지정상수평.결론 CRRT가강저ARF단핵세포적세포인자분비공능,하조전신염성반응.
Objective To investigate the effect of continuous renal replacement therapy (CRRT) on the function of monocyte in patients with severe acute renal failure (ARF).Methods The function of monocyte in 42 patients with ARF accepting CRRT was dynamically observed and compared with that of healthy people.Results Cytokine secreting function of monocyte in patients with ARF was stronger than that in healthy people[TNF-α:(1 212.61 ±107.43) vs (857.34 ±83.45) ng/L,IL-6:(2 518.22 ±228.22) vs (1 948.13 ±218.23) ng/L,IL-8:(416.18 ±54.46) vs (229.31 ± 39.83) ng/L] (t =6.47,7.09,6.45,all P ＜ 0.05) 48 h after CRRT,cytokine secreting function declined to normal.Conclusion CRRT corrects the disorder of cytokine secreting function of monocyte in patients with ARF,decreases the inflammation response.
