中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
2期
187-190
,共4页
乳腺肿瘤%危险因素%病例对照分析
乳腺腫瘤%危險因素%病例對照分析
유선종류%위험인소%병례대조분석
Breast neoplasms%Risk factors%Case-control study
目的 分析女性乳腺癌发病的危险因素,为乳腺癌的病因研究、高危人群的确定及制定有效的干预措施提供依据.方法 收集经病理证实为乳腺癌的患者,并筛选与乳腺癌患者年龄及生活环境相近健康女性,采用调查问卷收集乳腺癌相关危险因素,应用x2检验分析病例组及对照组相关因素的统计学差异,应用1∶2条件配对多因素logistic回归分析的相关危险因素与乳腺癌发病的相关性.结果 共184例乳腺癌患者及368例健康女性纳入研究.其中良性乳腺病史、母乳喂养、流产、心情压抑、吸烟、被动吸烟、经常吃豆制品、经常喝茶等因素在病例组及对照组差异有统计学意义；而良性乳腺病史(OR值=1.553,95％ CI 2.045～10.924)、流产史(OR值=0.775,95％ CI 1.423～3.309)、吸烟(OR值=0.674,95％CI 1.009～3.817)、被动吸烟(OR值=2.98,95％ CI 1.680 ～3.720)因素是乳腺癌发病的危险因素,而经常喝茶(OR值=-0.425,95％CI 0.446 ～0.958)、豆制品(OR值=-0.687,95％ CI 0.284 ～0.889)、母乳喂养(OR值=-0.827,95％,95％CI 0.193 ～0.991)为乳腺癌发病的保护因素.结论 女性乳腺癌发病危险因素包括良性乳腺病史、流产史、吸烟史、被动吸烟史,而经常喝茶、常吃豆制品、母乳喂养为乳腺癌发病的保护因素.
目的 分析女性乳腺癌髮病的危險因素,為乳腺癌的病因研究、高危人群的確定及製定有效的榦預措施提供依據.方法 收集經病理證實為乳腺癌的患者,併篩選與乳腺癌患者年齡及生活環境相近健康女性,採用調查問捲收集乳腺癌相關危險因素,應用x2檢驗分析病例組及對照組相關因素的統計學差異,應用1∶2條件配對多因素logistic迴歸分析的相關危險因素與乳腺癌髮病的相關性.結果 共184例乳腺癌患者及368例健康女性納入研究.其中良性乳腺病史、母乳餵養、流產、心情壓抑、吸煙、被動吸煙、經常喫豆製品、經常喝茶等因素在病例組及對照組差異有統計學意義；而良性乳腺病史(OR值=1.553,95％ CI 2.045～10.924)、流產史(OR值=0.775,95％ CI 1.423～3.309)、吸煙(OR值=0.674,95％CI 1.009～3.817)、被動吸煙(OR值=2.98,95％ CI 1.680 ～3.720)因素是乳腺癌髮病的危險因素,而經常喝茶(OR值=-0.425,95％CI 0.446 ～0.958)、豆製品(OR值=-0.687,95％ CI 0.284 ～0.889)、母乳餵養(OR值=-0.827,95％,95％CI 0.193 ～0.991)為乳腺癌髮病的保護因素.結論 女性乳腺癌髮病危險因素包括良性乳腺病史、流產史、吸煙史、被動吸煙史,而經常喝茶、常喫豆製品、母乳餵養為乳腺癌髮病的保護因素.
목적 분석녀성유선암발병적위험인소,위유선암적병인연구、고위인군적학정급제정유효적간예조시제공의거.방법 수집경병리증실위유선암적환자,병사선여유선암환자년령급생활배경상근건강녀성,채용조사문권수집유선암상관위험인소,응용x2검험분석병례조급대조조상관인소적통계학차이,응용1∶2조건배대다인소logistic회귀분석적상관위험인소여유선암발병적상관성.결과 공184례유선암환자급368례건강녀성납입연구.기중량성유선병사、모유위양、유산、심정압억、흡연、피동흡연、경상흘두제품、경상갈다등인소재병례조급대조조차이유통계학의의；이량성유선병사(OR치=1.553,95％ CI 2.045～10.924)、유산사(OR치=0.775,95％ CI 1.423～3.309)、흡연(OR치=0.674,95％CI 1.009～3.817)、피동흡연(OR치=2.98,95％ CI 1.680 ～3.720)인소시유선암발병적위험인소,이경상갈다(OR치=-0.425,95％CI 0.446 ～0.958)、두제품(OR치=-0.687,95％ CI 0.284 ～0.889)、모유위양(OR치=-0.827,95％,95％CI 0.193 ～0.991)위유선암발병적보호인소.결론 녀성유선암발병위험인소포괄량성유선병사、유산사、흡연사、피동흡연사,이경상갈다、상흘두제품、모유위양위유선암발병적보호인소.
Objective To explore the risk factors of female breast cancer and provide the basis for the etiology of female breast cancer,the identification of the high-risk population and the development of effective intervention measures.Methods The breast cancer patients who were confirmed by pathology were collected,and screened for healthy women whose age and living environment were similar to breast cancer patients.The questionnaire was used to collect risk-factors of breast cancer.The x2 test were used to analyze statistical difference of case group and control group.1 ∶ 2 logistic regression was used to analyze the relationship between risk factors and female breast cancer.Results There were 184 breast cancer patients and 368 healthy women in research.Benign breast disease,breastfeeding,abortion,depression,smoking,passive smoking,eating fried or smoked foods,drinking tea had statistical differences between case group and control group.And benign breast lesions(OR =1.553,95％ CI 2.045 ～ 10.924),abortion(OR =0.775,95 ％ CI 1.423 ～ 3.309),smoking(OR =0.674,95％ CI 1.009 ～ 3.817) passive smoking (OR =2.98,95％ CI 1.680 ～ 3.720) were the risk factors of breast cancer,and drink tea(OR =-0.425,95％ CI 0.446 ～ 0.958),eating soy products (OR =-0.687,95 ％ CI 0.284 ～ 0.889) breast-feeding (OR =-0.827,95％CI 0.193 ～ 0.991) were the protective factors of breast cancer.Conclusion The risk factors of female breast cancer in Binzhou are benign breast disease,abortion,passive smoking,depression,and the protective factors are drinking tea and breast-feeding.
