中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
2期
217-219,后插3
,共4页
头孢噻利%输液%配伍%高效液相色谱法%稳定性
頭孢噻利%輸液%配伍%高效液相色譜法%穩定性
두포새리%수액%배오%고효액상색보법%은정성
Cefoselis%Infusion%Campatibility%HPLC%Stability
目的 观察注射用硫酸头孢噻利与三种输液的配伍稳定性,为临床合理配伍使用提供依据.方法 在30℃下,将注射用硫酸头孢噻利分别与5％果糖注射液、果糖氯化钠注射液和转化糖注射液配伍,在6h内观察配伍液的外观、pH值变化,并采用高效液相色谱法测定三种配伍液中注射用硫酸头孢噻利的含量.结果 注射用硫酸头孢噻利与三种输液在6h内含量、pH值及外观均无明显变化.结论 注射用硫酸头孢噻利与三种输液在30℃,6h内配伍稳定.
目的 觀察註射用硫痠頭孢噻利與三種輸液的配伍穩定性,為臨床閤理配伍使用提供依據.方法 在30℃下,將註射用硫痠頭孢噻利分彆與5％果糖註射液、果糖氯化鈉註射液和轉化糖註射液配伍,在6h內觀察配伍液的外觀、pH值變化,併採用高效液相色譜法測定三種配伍液中註射用硫痠頭孢噻利的含量.結果 註射用硫痠頭孢噻利與三種輸液在6h內含量、pH值及外觀均無明顯變化.結論 註射用硫痠頭孢噻利與三種輸液在30℃,6h內配伍穩定.
목적 관찰주사용류산두포새리여삼충수액적배오은정성,위림상합리배오사용제공의거.방법 재30℃하,장주사용류산두포새리분별여5％과당주사액、과당록화납주사액화전화당주사액배오,재6h내관찰배오액적외관、pH치변화,병채용고효액상색보법측정삼충배오액중주사용류산두포새리적함량.결과 주사용류산두포새리여삼충수액재6h내함량、pH치급외관균무명현변화.결론 주사용류산두포새리여삼충수액재30℃,6h내배오은정.
Objective To investigate the compatible stability of cefoselis sulfate mixed with different kinds of transfusions(5％ fructose injection + cefoselis sulfate,fructose sodium chloride injection + cefoselis sufate and invert sugar injection + cefoselis sulfate).Methods At 30℃,the above different mixed solutions' appearance and pH changes within six hours were observed,and determine the concentration of cefoselis sulfate by HPLC.Results There were noobvious changes concern to the concentration,pH and appearance in the mixed solutions.Conclusion At 30℃,different cefoselis sulfate mixed injection all have good compatible stability within 6 hours.
