中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
3期
336-338
,共3页
体层摄影术,螺旋计算机%肿瘤移植%癌,肝细胞%化学栓塞,治疗性
體層攝影術,螺鏇計算機%腫瘤移植%癌,肝細胞%化學栓塞,治療性
체층섭영술,라선계산궤%종류이식%암,간세포%화학전새,치료성
Cicatrix,hypertrophic%Neoplasm transplantation%Carcinoma,hepatocell%Chemoembolization,therapeutic
目的 探讨双源双能量CT评价肝癌介入治疗疗效的价值.方法 8只生长良好的荷瘤兔,行介入手术,并进行双源双能量CT扫描,利用双源工作站OVERLAY信息图像,测量病灶区CT值,并记录其色阶变化,探讨双能量CT在肝癌介入治疗后肿瘤存活与坏死情况.结果 以全部的病理诊断为金标准,经过病理和影像对照分析,按黑色、暗红色、红色、橘红色顺序,色阶准确度分别为87.2％、72.3％、71.5％、83.6％,敏感度分别为95.1％、37.4％、54.7％、63.8％,特异度分别为85.4％、86.3％、81.5％、85.8％,阳性预测值分别为61.4％、54.2％、62.4％、55.6％,阴性预测值分别为96.3％ 、76.2％、79.7％、91.3％.行Spearman相关性分析,肿瘤细胞存活度与CT图像色阶变化呈正相关(r=12.35,P＜0.05).结论 双源双能量CT仅一次增强扫描,能够初步反映兔VX2移植瘤内肿瘤细胞坏死与存活的程度,为临床进一步诊疗提供良好的参考价值.
目的 探討雙源雙能量CT評價肝癌介入治療療效的價值.方法 8隻生長良好的荷瘤兔,行介入手術,併進行雙源雙能量CT掃描,利用雙源工作站OVERLAY信息圖像,測量病竈區CT值,併記錄其色階變化,探討雙能量CT在肝癌介入治療後腫瘤存活與壞死情況.結果 以全部的病理診斷為金標準,經過病理和影像對照分析,按黑色、暗紅色、紅色、橘紅色順序,色階準確度分彆為87.2％、72.3％、71.5％、83.6％,敏感度分彆為95.1％、37.4％、54.7％、63.8％,特異度分彆為85.4％、86.3％、81.5％、85.8％,暘性預測值分彆為61.4％、54.2％、62.4％、55.6％,陰性預測值分彆為96.3％ 、76.2％、79.7％、91.3％.行Spearman相關性分析,腫瘤細胞存活度與CT圖像色階變化呈正相關(r=12.35,P＜0.05).結論 雙源雙能量CT僅一次增彊掃描,能夠初步反映兔VX2移植瘤內腫瘤細胞壞死與存活的程度,為臨床進一步診療提供良好的參攷價值.
목적 탐토쌍원쌍능량CT평개간암개입치료료효적개치.방법 8지생장량호적하류토,행개입수술,병진행쌍원쌍능량CT소묘,이용쌍원공작참OVERLAY신식도상,측량병조구CT치,병기록기색계변화,탐토쌍능량CT재간암개입치료후종류존활여배사정황.결과 이전부적병리진단위금표준,경과병리화영상대조분석,안흑색、암홍색、홍색、귤홍색순서,색계준학도분별위87.2％、72.3％、71.5％、83.6％,민감도분별위95.1％、37.4％、54.7％、63.8％,특이도분별위85.4％、86.3％、81.5％、85.8％,양성예측치분별위61.4％、54.2％、62.4％、55.6％,음성예측치분별위96.3％ 、76.2％、79.7％、91.3％.행Spearman상관성분석,종류세포존활도여CT도상색계변화정정상관(r=12.35,P＜0.05).결론 쌍원쌍능량CT부일차증강소묘,능구초보반영토VX2이식류내종류세포배사여존활적정도,위림상진일보진료제공량호적삼고개치.
Objective To explore the diagnostic value of the dual-energy technique with dual-source in the evaluation of therapeutic effect of interventional therapy for hepatocarcinoma.Methods 8 rabbits with tumor growing well were treated with intervention operation,paralleled with double energy CT scan and focal area image,CT and color order change were measured by dual energy liver OVERLAY workstation.Meanwhile,The necrosis and survival of tumor were evaluated by dual energy CT after hepatocarcinoma intervention therapy.Results Taking pathologic diagnosis as gold standard,compared with imaging and pathological results in the order of black,red,orange and red,accuracies were 87.2％,72.3％,71.5％ and 83.6％ respectively.Sensitivities were 95.1％,37.4％,54.7％ and 63.8％ respectively.Specificities were 85.4％,86.3％,81.5％ and 85.8％ respectively.Positive predictives value were 61.4％,54.2％,62.4％ and 55.6％ respectively.Negative predictive values were 96.3％,76.2％,79.7％ and 91.3 ％ respectively.According to the Spearman relevance analysis,there was strong positive correlation between survival of tumor cells and image color scale (r =12.35,P ＜ 0.05).Conclusion The necrosis and survival of tumor cells in rabbit VX2 liver tumor model can be preliminarily reflected by dual source CT dual energy enhancement scanning.The results provide good reference to the application of dual-source and dual-energy in clinical diagnosis and treatment.
