CAJ | 학술논문

目的探讨地塞米松联合托烷司琼预防腹腔镜胆囊切除术后不良反应的临床价值.方法选取行腹腔镜胆囊切除术的患者1 500例,按照入院先后顺序随机分为单纯组与联合组各750例,单纯组采用托烷司琼,联合组采用地塞米松联合托烷司琼.结果术后24 h,单纯组疗效优良率为96％,联合组为100％,差异有统计学意义(x2=30.61,P＜0.05)；不良反应严重度评分,单纯组(4.1±1.8)分,联合组(2.0±1.1)分,两组差异有统计学意义(t =27.26,P＜0.05)；术后联合组头疼、眩晕、烦躁的发生率低于对照组(x2=94.35、26.79、78.95,均P＜0.05).结论地塞米松联合托烷司琼可以有效预防腹腔镜胆囊切除术后不良反应的发生,且降低不良反应程度,具有较高的临床应用价值.
목적 탐토지새미송연합탁완사경예방복강경담낭절제술후불량반응적림상개치.방법 선취행복강경담낭절제술적환자1 500례,안조입원선후순서수궤분위단순조여연합조각750례,단순조채용탁완사경,연합조채용지새미송연합탁완사경.결과 술후24 h,단순조료효우량솔위96％,연합조위100％,차이유통계학의의(x2=30.61,P＜0.05)；불량반응엄중도평분,단순조(4.1±1.8)분,연합조(2.0±1.1)분,량조차이유통계학의의(t =27.26,P＜0.05)；술후연합조두동、현훈、번조적발생솔저우대조조(x2=94.35、26.79、78.95,균P＜0.05).결론 지새미송연합탁완사경가이유효예방복강경담낭절제술후불량반응적발생,차강저불량반응정도,구유교고적림상응용개치.
Objective To explore the clinical value of dexamethasone combined with tropisetron in preventing adverse reaction after laparoscopic surgery.Methods According to the sequence of admission,1 500 laparoscopic cholecystectomy patients were divided into the simple group and compound group.The simple group was administrated with tropisetron,and the compound group was administrated with dexamethasone combined with tropisetron.Results 24h after opration,the excellent and good rate of the simple group was 96％,which of the compound group was 100％,there were significant differences between the two groups (x2 =30.61,P ＜ 0.05) ; The adverse reaction severity score of the simple group was (4.1 ± 1.8) points,which of the compound group was (2.0 ± 1.1) points,there were significant differences between the two groups (t =27.26,P ＜ 0.05) ; The incidence rates of headache,dizziness,irritability of the compound group were lower than those of the simple group (x2 =94.35,26.79,78.95,all P ＜ 0.05).Conclusion Dexamethasone combined with tropisetron is effective after laparoscopic surgery to prevent adverse reactions occur,and effectively reduce the adverse reaction degree,has a high clinical value,is worth the clinical attention.