中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
3期
369-370
,共2页
癌%骨转移%唑来膦酸%放疗
癌%骨轉移%唑來膦痠%放療
암%골전이%서래련산%방료
Carcinoma%Bony metastasis%Zoledronic acid%Radiotherapy
目的 探讨放疗+唑来膦酸对恶性肿瘤骨转移患者的临床治疗效果.方法 选取恶性肿瘤骨转移患者48例,随机分为治疗组与对照组各24例,对照组仅接受放疗,治疗组在放疗基础上加用唑来膦酸4 mg,每月1次,连用3～6次,3～6个月后评价骨痛缓解情况.结果 两组总有效率(83.3％和79.2％)差异无统计学意义(P＞0.05),但治疗组完全缓解(CR)率高于对照组(50.0％和33.3％,P＜0.05).两组间发热、骨髓抑制、肝肾功能等不良反应差异无统计学意义.结论 放疗+唑来膦酸治疗肿瘤骨转移CR率高,生活质量改善较明显,不良反应患者易接受,值得临床应用.
目的 探討放療+唑來膦痠對噁性腫瘤骨轉移患者的臨床治療效果.方法 選取噁性腫瘤骨轉移患者48例,隨機分為治療組與對照組各24例,對照組僅接受放療,治療組在放療基礎上加用唑來膦痠4 mg,每月1次,連用3～6次,3～6箇月後評價骨痛緩解情況.結果 兩組總有效率(83.3％和79.2％)差異無統計學意義(P＞0.05),但治療組完全緩解(CR)率高于對照組(50.0％和33.3％,P＜0.05).兩組間髮熱、骨髓抑製、肝腎功能等不良反應差異無統計學意義.結論 放療+唑來膦痠治療腫瘤骨轉移CR率高,生活質量改善較明顯,不良反應患者易接受,值得臨床應用.
목적 탐토방료+서래련산대악성종류골전이환자적림상치료효과.방법 선취악성종류골전이환자48례,수궤분위치료조여대조조각24례,대조조부접수방료,치료조재방료기출상가용서래련산4 mg,매월1차,련용3～6차,3～6개월후평개골통완해정황.결과 량조총유효솔(83.3％화79.2％)차이무통계학의의(P＞0.05),단치료조완전완해(CR)솔고우대조조(50.0％화33.3％,P＜0.05).량조간발열、골수억제、간신공능등불량반응차이무통계학의의.결론 방료+서래련산치료종류골전이CR솔고,생활질량개선교명현,불량반응환자역접수,치득림상응용.
Objective To explore the outcomes of radiotherapy and zoledronic acid in patients with bone metastasis.Methods 48 cancer patients with bone metastasis,were divided into two group,control group received radiotherapy only,therapy group received radiotherapy and zoledronic acid.Remission of ostalgia was evaluated after 3-6 months.Results The total effective of remission of ostalgia had no significant differences between two group(83.3 ％ vs 79.2％,P ＜ 0.05).But rate of complete remission therapy group was higher than that of control group(50.0％ vs 33.3％,P ＜ 0.05).The adverse reaction aer resemble between the two group.Conclusion The outcomes of radiotherapy and zoledronic acid in patients with bone metastasis is effectiveness for cases with bone metastasis,is worth spreading.
