中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
3期
389-391
,共3页
锌布颗粒%对乙酰氨基酚%发热%儿童
鋅佈顆粒%對乙酰氨基酚%髮熱%兒童
자포과립%대을선안기분%발열%인동
Zinc distribution of particles%Acetaminophen%Fever%Child
目的 比较锌布颗粒与对乙酰氨基酚治疗小儿发热的效果.方法 108例发热患儿,按随机数字表法分为观察组和对照组,每组54例.对照组给予对乙酰氨基酚,观察组给予复方锌布颗粒.比较两组疗效、体温变化、惊厥发生率和不良反应.结果 观察组总有效率为96.30％ (52/54),对照组为81.48％ (44/54),差异有统计学意义(x2=5.86,P＜0.05)；观察组服药后0.5h体温即较服药前显著下降(P＜0.05),对照组服药后1h开始较服药前显著下降(P＜0.05),观察组服药后0.5、1、2、4h体温均低于对照组(P＜0.05)；对照组不良反应发生率为12.96％ (7/54),观察组为11.11％ (6/54),差异无统计学意义(P＞0.05)；观察组惊厥发生率为3.70％ (2/54),对照组为14.81％ (8/54),差异有统计学意义(P＜0.05).结论 复方锌布颗粒治疗小儿发热较对乙酰氨基酚退热更快,持续时间更长,惊厥发生率低,不良反应少,值得临床推广应用.
目的 比較鋅佈顆粒與對乙酰氨基酚治療小兒髮熱的效果.方法 108例髮熱患兒,按隨機數字錶法分為觀察組和對照組,每組54例.對照組給予對乙酰氨基酚,觀察組給予複方鋅佈顆粒.比較兩組療效、體溫變化、驚厥髮生率和不良反應.結果 觀察組總有效率為96.30％ (52/54),對照組為81.48％ (44/54),差異有統計學意義(x2=5.86,P＜0.05)；觀察組服藥後0.5h體溫即較服藥前顯著下降(P＜0.05),對照組服藥後1h開始較服藥前顯著下降(P＜0.05),觀察組服藥後0.5、1、2、4h體溫均低于對照組(P＜0.05)；對照組不良反應髮生率為12.96％ (7/54),觀察組為11.11％ (6/54),差異無統計學意義(P＞0.05)；觀察組驚厥髮生率為3.70％ (2/54),對照組為14.81％ (8/54),差異有統計學意義(P＜0.05).結論 複方鋅佈顆粒治療小兒髮熱較對乙酰氨基酚退熱更快,持續時間更長,驚厥髮生率低,不良反應少,值得臨床推廣應用.
목적 비교자포과립여대을선안기분치료소인발열적효과.방법 108례발열환인,안수궤수자표법분위관찰조화대조조,매조54례.대조조급여대을선안기분,관찰조급여복방자포과립.비교량조료효、체온변화、량궐발생솔화불량반응.결과 관찰조총유효솔위96.30％ (52/54),대조조위81.48％ (44/54),차이유통계학의의(x2=5.86,P＜0.05)；관찰조복약후0.5h체온즉교복약전현저하강(P＜0.05),대조조복약후1h개시교복약전현저하강(P＜0.05),관찰조복약후0.5、1、2、4h체온균저우대조조(P＜0.05)；대조조불량반응발생솔위12.96％ (7/54),관찰조위11.11％ (6/54),차이무통계학의의(P＞0.05)；관찰조량궐발생솔위3.70％ (2/54),대조조위14.81％ (8/54),차이유통계학의의(P＜0.05).결론 복방자포과립치료소인발열교대을선안기분퇴열경쾌,지속시간경장,량궐발생솔저,불량반응소,치득림상추엄응용.
Objective To compare the effect of zinc distribution of particles and acetaminophen treats pediatric fever.Methods 108 children with fever were randomly divided into the observation group and the control group,54 cases in each group.The control group was given paracetamol,the observation group was given cloth compound of zinc particles.Efficacy of temperature changes,seizures and the incidence of adverse reaction were compared in two groups.Results The total effective was 96.30％ (52/54) in the observation group,the control group was 81.48％ (44/54),there were no significant differences (x2 =5.86,P ＜ 0.05).The body temperature is remarkably reduced after taking medicine for 0.5h in the observation group (P ＜ 0.05).The body temperature is remarkably reduced after taking medicine for lh in the control group (P ＜ 0.05).The body temperature is remarkably reduced after taking medicine for 0.5,1,2,4 h in the observation group which were lower than those of the control group (P ＜0.05).The incidence of adverse reactions was 12.96％ (7/54) in the control group,which was 11.11％ (6/54) in the observation group,there were no significant differences (P ＞ 0.05).The convulsion rate ioas 3.70％ (2/54) in the observation group,which was 14.81％ (8/54) in the control group,there were no significant differences (P ＜0.05).Conclusion It is faster,longer duration,seizure occurs at a low rate for the cloth compound of zinc particles treats pediatric fever than acetaminophen antipyretic.It is worthy of clinical application.
