中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
5期
678-680
,共3页
杨振涛%刘会恩%张万峰%王洪杰%丁晓晖%李明%王百峰
楊振濤%劉會恩%張萬峰%王洪傑%丁曉暉%李明%王百峰
양진도%류회은%장만봉%왕홍걸%정효휘%리명%왕백봉
膀胱癌%淋巴转移%血管内皮生长因子-C%血管内皮生长因子受体-3
膀胱癌%淋巴轉移%血管內皮生長因子-C%血管內皮生長因子受體-3
방광암%림파전이%혈관내피생장인자-C%혈관내피생장인자수체-3
Bladder cancer%Lymph node,metastasis%Vascular endothelial growth factor-C%Vascular endothelial growth factor receptor-3
目的 探讨血管内皮生长因子-C(VEGF-C)、血管内皮生长因子受体3(VEGFR-3)在膀胱癌组织中的表达与肿瘤淋巴转移的关系.方法 采用ElivisionTM Plus二步法检测膀胱癌组织中VEGF-C、VEG-FR-3的表达情况.结果 在18例膀胱癌组织中,VEGF-C表达阳性率为72％,VEGFR-3表达阳性率为67％.VEGF-C在膀胱癌转移的淋巴结中的表达水平较未发生转移的淋巴结高.结论 在膀胱癌组织及周围淋巴结中,VEGF-C、VEGFR-3的表达水平与淋巴转移密切相关,VEGF-C、VEGFR-3的表达强度可作为膀胱癌淋巴结转移的判断指标之一.
目的 探討血管內皮生長因子-C(VEGF-C)、血管內皮生長因子受體3(VEGFR-3)在膀胱癌組織中的錶達與腫瘤淋巴轉移的關繫.方法 採用ElivisionTM Plus二步法檢測膀胱癌組織中VEGF-C、VEG-FR-3的錶達情況.結果 在18例膀胱癌組織中,VEGF-C錶達暘性率為72％,VEGFR-3錶達暘性率為67％.VEGF-C在膀胱癌轉移的淋巴結中的錶達水平較未髮生轉移的淋巴結高.結論 在膀胱癌組織及週圍淋巴結中,VEGF-C、VEGFR-3的錶達水平與淋巴轉移密切相關,VEGF-C、VEGFR-3的錶達彊度可作為膀胱癌淋巴結轉移的判斷指標之一.
목적 탐토혈관내피생장인자-C(VEGF-C)、혈관내피생장인자수체3(VEGFR-3)재방광암조직중적표체여종류림파전이적관계.방법 채용ElivisionTM Plus이보법검측방광암조직중VEGF-C、VEG-FR-3적표체정황.결과 재18례방광암조직중,VEGF-C표체양성솔위72％,VEGFR-3표체양성솔위67％.VEGF-C재방광암전이적림파결중적표체수평교미발생전이적림파결고.결론 재방광암조직급주위림파결중,VEGF-C、VEGFR-3적표체수평여림파전이밀절상관,VEGF-C、VEGFR-3적표체강도가작위방광암림파결전이적판단지표지일.
Objective To explore vascular endothelial growth factor-C (VEGF-C),vascular endothelial growth factor receptor 3 (VEGFR-3) in the bladder cancer tissue of the expression and the relationship with the tumor lymph node metastases of bladder cancer tissue,Methods The VEGF-C,VEGFR-3 expression was detected by Elivision TM plus two footwork.Results In 18 cases of bladder cancer organization,VEGF-C expression positive rate was 72％,VEGFR-3 express positive rate was 67％.VEGF-C in the bladder cancer of the transfer of the expression level compared to the lymph nodes of the transfer of the lymph node has not occurred to high.Conclusion In the bladder cancer organization and the surroundinglymph nodes,VEGF-C,VEGFR-3 expression level and lymph node metastasis is closely related.VEGF-C,VEGFR-3 expression intensity can be used as a lymph node metastasis in bladder cancer index.
