CAJ | 학술논문

目的探讨肝硬化合并糖尿病的发病机制、临床特点及治疗措施.方法对32例肝硬化合并糖尿病患者的临床资料进行回顾性分析.结果 136例肝硬化患者合并肝源性糖尿病32例(23.5％),32例肝源性糖尿病患者,无糖尿病家族史,发现糖尿病前均患有慢性肝病导致肝硬化,其糖尿病临床表现不典型,空腹血糖以轻、中度升高为主,控制饮食、改善肝功能及口服降血糖药物或胰岛素治疗有效.结论肝硬化患者易发生糖代谢紊乱,发生机制可能与胰岛素抵抗有关,血糖水平与肝功能受损程度有一定关系.治疗上以保肝治疗为主,兼顾控制血糖,多数预后良好.
목적 탐토간경화합병당뇨병적발병궤제、림상특점급치료조시.방법 대32례간경화합병당뇨병환자적림상자료진행회고성분석.결과 136례간경화환자합병간원성당뇨병32례(23.5％),32례간원성당뇨병환자,무당뇨병가족사,발현당뇨병전균환유만성간병도치간경화,기당뇨병림상표현불전형,공복혈당이경、중도승고위주,공제음식、개선간공능급구복강혈당약물혹이도소치료유효.결론 간경화환자역발생당대사문란,발생궤제가능여이도소저항유관,혈당수평여간공능수손정도유일정관계.치료상이보간치료위주,겸고공제혈당,다수예후량호.
Objective To explore the pathogenicity and clinic character and treatment of patients with hepatic cirrhosis and diabetes mellitus.Methods Retrospectively analyzed clinic date of 32 cases with hepatic cirrhosis and diabetes mellitus.Results Among the 136 patients with cirrhosis,there were 32 patients having hepatogenous diabetes (which accounts for 23.5％).In the 32 patients with hepatogenous diabetes we found the patients with no family history of diabetes and before patients foured out that they were diabetic.The clinical manifestation of the diabetes was not typical.The main manifestation was that the glucose was low or moderately elevated when they were in empty stomach.The effective treatments for controlling diet,improving liver function and taking hypoglycemic medicine orally or injecting insulin.Conclusion Patients with cirrhosis tend to have disorders in their metabolism of carbohydrates,which might be related to the body resistance of insulin,glucose levels and the degree of the damage of their liver function.The treatment should emphasize on protecting the liver while controlling glucose level.Most cases have good recovery.