中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
6期
860-862
,共3页
冠状动脉疾病%高半胱氨酸%C反应蛋白质%脂蛋白(A)%D-二聚体
冠狀動脈疾病%高半胱氨痠%C反應蛋白質%脂蛋白(A)%D-二聚體
관상동맥질병%고반광안산%C반응단백질%지단백(A)%D-이취체
Coronary disease%Homocysteine%C-reactive protein%Lipoprotein (a)%D-two dimer
目的 探讨同型半胱氨酸(Hcy)、超敏C-反应蛋白(hs-CRP)、脂蛋白(a)[LP(a)]和D-二聚体(DD)联合检测在冠心病诊疗中的应用价值.方法 对180例冠心病患者(冠心病组)和同期来该院体检合格的健康人200例(对照组)分别检测Hcy、hs-CRP、LP(a)和DD水平,比较两组各项检测指标的差异.结果 冠心病组Hcy、hs-CRP、LP(a)和DD含量均明显高于对照组(t=13.87、10.24、9.86、18.02,均P＜0.05).冠心病患者各组间各项指标比较:AMI组明显高于UAP组(t=15.79、9.73、11.47、17.34,均P＜0.05)、UAP组明显高于SAP组(t=16.82、8.14、10.65、18.27,均P＜0.05)、SAP组明显高于SMI组(t=14.36、10.35、9.98、16.52,均P＜0.05).结论 对冠心病患者血清Hcy、hs-CRP、LP(a)和DD联合检测有助于了解冠心病病程发展,评估冠心病风险.
目的 探討同型半胱氨痠(Hcy)、超敏C-反應蛋白(hs-CRP)、脂蛋白(a)[LP(a)]和D-二聚體(DD)聯閤檢測在冠心病診療中的應用價值.方法 對180例冠心病患者(冠心病組)和同期來該院體檢閤格的健康人200例(對照組)分彆檢測Hcy、hs-CRP、LP(a)和DD水平,比較兩組各項檢測指標的差異.結果 冠心病組Hcy、hs-CRP、LP(a)和DD含量均明顯高于對照組(t=13.87、10.24、9.86、18.02,均P＜0.05).冠心病患者各組間各項指標比較:AMI組明顯高于UAP組(t=15.79、9.73、11.47、17.34,均P＜0.05)、UAP組明顯高于SAP組(t=16.82、8.14、10.65、18.27,均P＜0.05)、SAP組明顯高于SMI組(t=14.36、10.35、9.98、16.52,均P＜0.05).結論 對冠心病患者血清Hcy、hs-CRP、LP(a)和DD聯閤檢測有助于瞭解冠心病病程髮展,評估冠心病風險.
목적 탐토동형반광안산(Hcy)、초민C-반응단백(hs-CRP)、지단백(a)[LP(a)]화D-이취체(DD)연합검측재관심병진료중적응용개치.방법 대180례관심병환자(관심병조)화동기래해원체검합격적건강인200례(대조조)분별검측Hcy、hs-CRP、LP(a)화DD수평,비교량조각항검측지표적차이.결과 관심병조Hcy、hs-CRP、LP(a)화DD함량균명현고우대조조(t=13.87、10.24、9.86、18.02,균P＜0.05).관심병환자각조간각항지표비교:AMI조명현고우UAP조(t=15.79、9.73、11.47、17.34,균P＜0.05)、UAP조명현고우SAP조(t=16.82、8.14、10.65、18.27,균P＜0.05)、SAP조명현고우SMI조(t=14.36、10.35、9.98、16.52,균P＜0.05).결론 대관심병환자혈청Hcy、hs-CRP、LP(a)화DD연합검측유조우료해관심병병정발전,평고관심병풍험.
Objective To study the meaning of Homocysteine,serum high sensitive C-reactive protein,lipoprotein A and D-two dimer combined detection in the course of coronary heart disease.Methods Select 180 cases suffering from different types of coronary heart disease as group of coronary heart disease,200 healthy people who were in our hospital physical examination qualified over the same period as the control group,all the cases of fasting venous blood was sampled respectively to detect the content of Hcy,hs-CRP,LP(a) and DD.Results Coronary heart disease group of patients with Hcy,hs-CRP,LP(a) and DD levels were significantly higher than those of the control group of healthy persons(t =13.87,10.24,9.86,18.02,P ＜ 0.05),Comparison among different indicators of the patiens with Coronary heart disease:the group of AMI was higher than the group of UAP (t =15.79,9.73,11.47,17.34,all P ＜ 0.05),the group of UAP was higher than the group of SAP (t =16.82,8.14,10.65,18.27,P ＜0.05),the group of SAP was higher than the group of SMI (t =14.36,10.35,9.98,16.52,P ＜ 0.05).Conclusion Monitoring of Hcy,hs-CRP,LP(a) and DD for coronary heart disease,contributes to the understand of the development of the course of coronary heart disease and assess the risk of coronary heart disease.
