中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
7期
996-998
,共3页
肾病综合征%复发%危险因素%因果律%儿童
腎病綜閤徵%複髮%危險因素%因果律%兒童
신병종합정%복발%위험인소%인과률%인동
Nephrotic syndrome%Recurrence%Risk factors%Causality%Child
目的 探讨复发型小儿原发性肾病综合征发生的相关影响因素,为其临床的防治提供参考.方法 共纳入120例小儿原发性肾病综合征患者,根据其是否为复发型分为两组,详细记录两组患者的基本信息,应用多因素回归分析进行多因素分析.结果 120例小儿原发性肾病综合征患儿中有20例患儿随访1年内复发,复发发生率为16.7％.单因素分析结果显示:反复感染、使用白蛋白≥2次、采用短程治疗、白蛋白水平及血清IgG水平与复发型小儿原发性肾病综合征的发生存在密切的相关性,两组差异有统计学意义(P＜0.05).多因素分析结果表明:反复感染、使用白蛋白≥2次及白蛋白水平低下是引起复发型小儿原发性肾病综合征发生的独立危险因素(P＜0.05).结论 小儿原发性肾病综合征发生复发的独立危险因素主要包括反复感染、使用白蛋白≥2次及白蛋白水平的低下,在临床工作中对于上述可干预的危险因素进行必要的干预有重要的意义,可降低患儿复发的风险.
目的 探討複髮型小兒原髮性腎病綜閤徵髮生的相關影響因素,為其臨床的防治提供參攷.方法 共納入120例小兒原髮性腎病綜閤徵患者,根據其是否為複髮型分為兩組,詳細記錄兩組患者的基本信息,應用多因素迴歸分析進行多因素分析.結果 120例小兒原髮性腎病綜閤徵患兒中有20例患兒隨訪1年內複髮,複髮髮生率為16.7％.單因素分析結果顯示:反複感染、使用白蛋白≥2次、採用短程治療、白蛋白水平及血清IgG水平與複髮型小兒原髮性腎病綜閤徵的髮生存在密切的相關性,兩組差異有統計學意義(P＜0.05).多因素分析結果錶明:反複感染、使用白蛋白≥2次及白蛋白水平低下是引起複髮型小兒原髮性腎病綜閤徵髮生的獨立危險因素(P＜0.05).結論 小兒原髮性腎病綜閤徵髮生複髮的獨立危險因素主要包括反複感染、使用白蛋白≥2次及白蛋白水平的低下,在臨床工作中對于上述可榦預的危險因素進行必要的榦預有重要的意義,可降低患兒複髮的風險.
목적 탐토복발형소인원발성신병종합정발생적상관영향인소,위기림상적방치제공삼고.방법 공납입120례소인원발성신병종합정환자,근거기시부위복발형분위량조,상세기록량조환자적기본신식,응용다인소회귀분석진행다인소분석.결과 120례소인원발성신병종합정환인중유20례환인수방1년내복발,복발발생솔위16.7％.단인소분석결과현시:반복감염、사용백단백≥2차、채용단정치료、백단백수평급혈청IgG수평여복발형소인원발성신병종합정적발생존재밀절적상관성,량조차이유통계학의의(P＜0.05).다인소분석결과표명:반복감염、사용백단백≥2차급백단백수평저하시인기복발형소인원발성신병종합정발생적독립위험인소(P＜0.05).결론 소인원발성신병종합정발생복발적독립위험인소주요포괄반복감염、사용백단백≥2차급백단백수평적저하,재림상공작중대우상술가간예적위험인소진행필요적간예유중요적의의,가강저환인복발적풍험.
Objective To explore the relapse type pediatric primary nephrotic syndrome happened related influencing factors,and to provide the reference of the clinical prevention and control.Methods Participants included 120 cases of primary nephrotic syndrome patients,according to its whether for relapse type divided into two groups,a detailed record of two groups of patients with basic information,the application of multiple factors regression analysis with factor analysis.Results 120 cases of primary nephrotic syndrome in children with 20 cases follow-up of 1 year relapse occurred,the recurrence rate was 16.7％.Single factor analysis results show that repeated infection,use of albumin was 2 times,use short treatment,the serum albumin level and IgG levels and relapse type pediatric primary nephrotic syndrome happened there was a close correlation,there was difference between the two groups (P ＜ 0.05).Multiple factors analysis results showed that repeated infection,use of albumin was 2 times and the low level of albumin is cause recrudesce type pediatric primary nephrotic syndrome happened independent risk factors (P ＜ 0.05).Conclusion Pediatric primary nephrotic syndrome recurrence occurred independent risk factors include repeated infection,use of albumin was 2 times and albumin level is low,in the clinical work for the above can intervention risk factors necessary intervention has important meaning,can reduce the risk of recurrence of children.
