CAJ | 학술논문

目的观察右美托咪定(DEX)在小儿腹股沟斜疝手术镇静效果及对氯胺酮基础麻醉的不良反应的影响.方法 80例行腹股沟斜疝修补手术的患儿采用咪达唑仑复合氯胺酮基础麻醉,然后按随机数字表法分为两组,对照组静脉注射0.9％氯化钠注射液,DEX组静脉注射0.5μg/kg DEX,用利多卡因骶管阻滞.观察患儿血流动力学、术中镇静程度、苏醒时间、苏醒期躁动评分,记录不良反应.结果两组血流动力学稳定,苏醒时间差异无统计学意义,镇静评分对照组(1.6±0.5)分大于DEX组(0.9±0.3)分(P＜0.05),苏醒期躁动评分对照组(1.52±0.54)分大于DEX组(0.51±0.48)分(P＜0.05),与DEX组比较,对照组出现6例严重躁动,12例精神症状,10例不自主肢体活动,8例恶心呕吐(P＜0.05).结论结论0.5 μg/kgDEX可以安全有效用于小儿麻醉,而且降低氯胺酮所引起的不良反应.
목적 관찰우미탁미정(DEX)재소인복고구사산수술진정효과급대록알동기출마취적불량반응적영향.방법 80례행복고구사산수보수술적환인채용미체서륜복합록알동기출마취,연후안수궤수자표법분위량조,대조조정맥주사0.9％록화납주사액,DEX조정맥주사0.5μg/kg DEX,용리다잡인저관조체.관찰환인혈류동역학、술중진정정도、소성시간、소성기조동평분,기록불량반응.결과 량조혈류동역학은정,소성시간차이무통계학의의,진정평분대조조(1.6±0.5)분대우DEX조(0.9±0.3)분(P＜0.05),소성기조동평분대조조(1.52±0.54)분대우DEX조(0.51±0.48)분(P＜0.05),여DEX조비교,대조조출현6례엄중조동,12례정신증상,10례불자주지체활동,8례악심구토(P＜0.05).결론 결론0.5 μg/kgDEX가이안전유효용우소인마취,이차강저록알동소인기적불량반응.
Objective To study dexmedetomidine on the adverse impact of ketamine based anesthesia and sedative effects in indirect inguinal hemia.Methods Eighty children underwent indirect inguinal hemia surgery were randomily divided into two groups after injected muscle with midazolam and ketamine,Group B was injectded with 0.5 μg/kg DEX,but Group A with normal saline,analgesia was with caudal block (lidocaine).The with hemodynamic,level of sedation,recovery time and CHW score were observed.The adverse reactions were recorded.Results Two groups of children have hemodynamically stable,and recovery time had no statistical significance.The two groups of CHW score in Group A (1.6 ± 0.5) points higher than in group B (0.9 ± 0.3) points (P ＜ 0.05).The restlessness rated group (1.52 ± 0.54) points was higher than in group B (0.51 ± 0.48) points (P ＜ 0.05).Compared with Group B,Group A had 12 cases of psychiatric symptoms,10 cases of involuntary movement of limbs,6 cases of severe postoperative agitation nausea,and 8 cases of vomiting (P ＜ 0.05).Conclusion 0.5μg/kg DEX can be safely and effectively used in the pediatric anesthesia,and reduce the adverse reactions caused by ketamine.