中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
8期
1127-1128
,共2页
阿托伐他汀%脑梗死%神经功能
阿託伐他汀%腦梗死%神經功能
아탁벌타정%뇌경사%신경공능
Atorvastatin%Cerebral infarction%Neurological function
目的 探讨阿托伐他汀对进展性脑梗死患者神经功能的影响.方法 选择进展性脑梗死患者80例,随机分为两组,对照组40例采用常规治疗,观察组40例在此基础上加用阿托伐他汀治疗,并对两组临床资料进行回顾性分析.结果 两组神经功能缺损评分治疗前差异无统计学意义,治疗后观察组显著高于对照组,差异有统计学意义(P＜0.05).观察组40例中,痊愈23例(57.5％),显效10例(25.0％),有效5例(12.5％),无效2例(5.0％),临床总有效率为95％；对照组40例中,痊愈9例(22.5％),显效9例(22.5％),有效10例(25.0％),无效12例(30.0％),总有效率为70％.观察组总有效率显著优于对照组,差异有统计学意义(P＜0.05).结论 进展性脑梗死患者在常规抗凝的基础上加用阿托伐他汀治疗,可最大限度地保护神经功能,提高临床治愈率,改善患者生存质量.
目的 探討阿託伐他汀對進展性腦梗死患者神經功能的影響.方法 選擇進展性腦梗死患者80例,隨機分為兩組,對照組40例採用常規治療,觀察組40例在此基礎上加用阿託伐他汀治療,併對兩組臨床資料進行迴顧性分析.結果 兩組神經功能缺損評分治療前差異無統計學意義,治療後觀察組顯著高于對照組,差異有統計學意義(P＜0.05).觀察組40例中,痊愈23例(57.5％),顯效10例(25.0％),有效5例(12.5％),無效2例(5.0％),臨床總有效率為95％；對照組40例中,痊愈9例(22.5％),顯效9例(22.5％),有效10例(25.0％),無效12例(30.0％),總有效率為70％.觀察組總有效率顯著優于對照組,差異有統計學意義(P＜0.05).結論 進展性腦梗死患者在常規抗凝的基礎上加用阿託伐他汀治療,可最大限度地保護神經功能,提高臨床治愈率,改善患者生存質量.
목적 탐토아탁벌타정대진전성뇌경사환자신경공능적영향.방법 선택진전성뇌경사환자80례,수궤분위량조,대조조40례채용상규치료,관찰조40례재차기출상가용아탁벌타정치료,병대량조림상자료진행회고성분석.결과 량조신경공능결손평분치료전차이무통계학의의,치료후관찰조현저고우대조조,차이유통계학의의(P＜0.05).관찰조40례중,전유23례(57.5％),현효10례(25.0％),유효5례(12.5％),무효2례(5.0％),림상총유효솔위95％；대조조40례중,전유9례(22.5％),현효9례(22.5％),유효10례(25.0％),무효12례(30.0％),총유효솔위70％.관찰조총유효솔현저우우대조조,차이유통계학의의(P＜0.05).결론 진전성뇌경사환자재상규항응적기출상가용아탁벌타정치료,가최대한도지보호신경공능,제고림상치유솔,개선환자생존질량.
Objective To explore the influence of atorvastatin on neurological function of patients with progressive cerebral infarction.Methods 80 patients with cerebral infarction were randomly divided into two groups,40 cases in the control group using conventional treatment,the observation group 40 cases on the basis of control group combined with atorvastatin treatment.Two groups of clinical data were retrospectively analyzed.Results Two groups of neural function defect score before treatment had no significant difference,after treatment,observation group scored significantly higher than that of control group,the difference was statistically significant (P ＜ 0.05).The observation group 40 cases,23 cases were cured,57.5％ ; 10 cases,accounting for 25.0％ ; effective 5 cases,accounting for 12.5％,2 cases are invalid,accounted for 5.0％,the total clinical efficiency of 95.0％.40 cases in the control group,9 cases were cured,22.5％ ;9 cases,accounting for 22.5 ％ ; effective in 10 cases,accounting for 25.0％,12,30.0％.The total efficiency was 70.0％.The total efficiency of observation group was better than that of the control group,the difference was statistically significant (P ＜ 0.05).Conclusion The progress of cerebral infarction patients in the conventional anticoagulation plus atorvastatin,which can maximize the protection of nerve function,improve the clinical cure rate and improve the life quality of the patients.
