中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
12期
1788-1790
,共3页
肾小球滤过率%99m Tc-DTPA清除率%胱抑素C%肌酐%尿素氮%成年人
腎小毬濾過率%99m Tc-DTPA清除率%胱抑素C%肌酐%尿素氮%成年人
신소구려과솔%99m Tc-DTPA청제솔%광억소C%기항%뇨소담%성년인
Glomerular filtration rate%Clearance rate of 99mTc-DTPA%Cystatin C%Creatinine%Blood urea nitrogen%Adult
目的 探讨成年人肾小球滤过率估算新公式(AC-eGFR)的临床应用价值.方法 用99mTc-DTPA清除率准确测定117例不同疾病住院患者肾小球滤过率(Tc-GFR),并用生化仪测定血清胱抑素C、肌酐及尿素氮,同时以AC-eGFR、CKD-EPI等11条公式计算GFR,所得数据进行相关分析与对比研究.结果 11条公式的肾小球滤过率估算值均能在一定程度上准确反映肾小球滤过率,而以AC-eGFR、CKD-EPI-eGFR与Larsson A et al-eGFR更准确,可代替Tc-GFR应用于临床,Robert TT-eGFR、Filler Get al-eGFR与Grubb A et aleGFR稍差.结论 AC-eGFR、CKD-EPI-eGFR、Larsson A et al-eGFR等公式均为准确、简便、快速、安全、廉价而合理的检测成年人肾小球滤过率方法,值得临床推广应用.
目的 探討成年人腎小毬濾過率估算新公式(AC-eGFR)的臨床應用價值.方法 用99mTc-DTPA清除率準確測定117例不同疾病住院患者腎小毬濾過率(Tc-GFR),併用生化儀測定血清胱抑素C、肌酐及尿素氮,同時以AC-eGFR、CKD-EPI等11條公式計算GFR,所得數據進行相關分析與對比研究.結果 11條公式的腎小毬濾過率估算值均能在一定程度上準確反映腎小毬濾過率,而以AC-eGFR、CKD-EPI-eGFR與Larsson A et al-eGFR更準確,可代替Tc-GFR應用于臨床,Robert TT-eGFR、Filler Get al-eGFR與Grubb A et aleGFR稍差.結論 AC-eGFR、CKD-EPI-eGFR、Larsson A et al-eGFR等公式均為準確、簡便、快速、安全、廉價而閤理的檢測成年人腎小毬濾過率方法,值得臨床推廣應用.
목적 탐토성년인신소구려과솔고산신공식(AC-eGFR)적림상응용개치.방법 용99mTc-DTPA청제솔준학측정117례불동질병주원환자신소구려과솔(Tc-GFR),병용생화의측정혈청광억소C、기항급뇨소담,동시이AC-eGFR、CKD-EPI등11조공식계산GFR,소득수거진행상관분석여대비연구.결과 11조공식적신소구려과솔고산치균능재일정정도상준학반영신소구려과솔,이이AC-eGFR、CKD-EPI-eGFR여Larsson A et al-eGFR경준학,가대체Tc-GFR응용우림상,Robert TT-eGFR、Filler Get al-eGFR여Grubb A et aleGFR초차.결론 AC-eGFR、CKD-EPI-eGFR、Larsson A et al-eGFR등공식균위준학、간편、쾌속、안전、렴개이합리적검측성년인신소구려과솔방법,치득림상추엄응용.
Objective To explore the clinical application value of the new formula for estimating glomerular filtration rate(eGFR) for adult Chinese(AC-eGFR).Methods GFR from 117 patients in hospital suffering from the difference diseases was determined accurately using clearance rate of 99mTc-DTPA(Tc-GFR).The serum cystatin C,creatinine and blood urea nitrogen were determined by the biochemical apparatus.Simultaneously,GFR was calculated by the eleven formulas such as AC-eGFR,CKD-EPI formula etc..Then,the results were compared and analyzed.Results eGFR from the eleven formulas could all give expression to GFR accurately in some extent,AC-eGFR,CKDEPI-eGFR and Larsson A et al-eGFR were more accurate than others and could take place of Tc-GFR clinically.Robert TT-eGFR,Filler Get al-eGFR and Grubb Aet al-eGFR were worse than others.Conclusion AC-eGFR,CKDEPI-eGFR and Larsson A et al-eGFR were all accurate,simple,fast,safe,cheap and rational method for estimatingGFR,which should apply and popularize clinically.
