CAJ | 학술논문

目的探讨葛根素与硫辛酸联合治疗2型糖尿病患者周围神经病变的临床疗效.方法选取2型糖尿病伴发周围神经病变患者80例,按照用药不同将其分为单药对照治疗组(硫辛酸)和联合用药治疗组(葛根素+硫辛酸).观察两组治疗后血糖水平、山梨醇检测值、糖化血红蛋白水平和神经传导速度等.结果治疗组有效率高于对照组,神经传导速度、血糖水平、山梨醇检测值、糖化血红蛋白水平优于对照组,差异均有统计学意义(均P＜0.05).结论葛根素联合用药能显著改善患者的周围神经病变症状,疗效较好.
목적 탐토갈근소여류신산연합치료2형당뇨병환자주위신경병변적림상료효.방법 선취2형당뇨병반발주위신경병변환자80례,안조용약불동장기분위단약대조치료조(류신산)화연합용약치료조(갈근소+류신산).관찰량조치료후혈당수평、산리순검측치、당화혈홍단백수평화신경전도속도등.결과 치료조유효솔고우대조조,신경전도속도、혈당수평、산리순검측치、당화혈홍단백수평우우대조조,차이균유통계학의의(균P＜0.05).결론 갈근소연합용약능현저개선환자적주위신경병변증상,료효교호.
Objective To analyze the clinical effect of puerarin and lipoic acid in treatment diabetic peripheral neuropathy.Methods 80 type Ⅱ diabetes patients accompanied with peripheral neuropathy were selected.According to different therapy,they were divided into single drug treatment control group (lipoic acid) and combined treatment group (puerarin + lipoie acid).Total effective rate,MNCV,SNCV,FBG,HbAlc and sorbitol were evaluated after treatment.Results The total effective rate in the treatment group was higher than that in the control group (P ＜ 0.05).Compared with the control group,the recovery rates of MNCV and SNCV were faster in the treatment group(P ＜0.05).And the levels of FBG,HbAlc and sorbitol were significantly lower in the treatment group than in the control group(P ＜ 0.05).Concluslon The clinical effect of puerarin and lipoic acid in treatment diabetic peripheral neuropathy was significant.