CAJ | 학술논문

目的探讨手术前后肠内营养支持对合并营养风险胃癌患者营养状况的影响.方法将有营养风险的72例胃癌患者采用随机数字表法分为两组,肠外营养组(PN组)36例,行术后常规静脉营养支持；肠内营养组(EN组)36例,从术前第5天到术后第8天给予肠内营养支持.两组均于术前第5天、术晨、术后第1天和术后第8天测量体质量,测定血清总蛋白、白蛋白、转铁蛋白和前白蛋白.结果 EN组术晨转铁蛋白和前白蛋白水平高于PN组(P＜0.05)；术后第8天,EN组体质量、总蛋白、白蛋白、转铁蛋白和前白蛋白均高于PN组(均P＜0.05)；EN组术晨转铁蛋白和前白蛋白均较术前第5天升高,差异均有统计学意义(P＜0.01).结论手术前后肠内营养支持可以改善合并营养风险胃癌患者的营养状况.而术前进食肠内营养,可以提高胃癌患者术前营养状况,改善术前的营养储备,降低术后肠内营养的不良反应.
목적 탐토수술전후장내영양지지대합병영양풍험위암환자영양상황적영향.방법 장유영양풍험적72례위암환자채용수궤수자표법분위량조,장외영양조(PN조)36례,행술후상규정맥영양지지；장내영양조(EN조)36례,종술전제5천도술후제8천급여장내영양지지.량조균우술전제5천、술신、술후제1천화술후제8천측량체질량,측정혈청총단백、백단백、전철단백화전백단백.결과 EN조술신전철단백화전백단백수평고우PN조(P＜0.05)；술후제8천,EN조체질량、총단백、백단백、전철단백화전백단백균고우PN조(균P＜0.05)；EN조술신전철단백화전백단백균교술전제5천승고,차이균유통계학의의(P＜0.01).결론 수술전후장내영양지지가이개선합병영양풍험위암환자적영양상황.이술전진식장내영양,가이제고위암환자술전영양상황,개선술전적영양저비,강저술후장내영양적불량반응.
Objective To investigate the significance of preoperative and postoperative enteral nutrition support in gastric cancer patients with nutritional risk.Methods The clinical data of 72 gastric cancer patients with nutritional risk admitted in our department were analyzed.All the patients were randomly allocated into two groups.36 patients in the control group received only intravenous nutrition postoperatively (PN group).36 patients in the treatment group received enteral nutrition support from the fifth day before operation to eighth day after operation (EN group).The body weight,total protein,albumin,transferrin and prealbumin were measured on the fifth day before operation,the operation morning,the first day and the eighth day after operation.Results On the operation morning,the transferrin and prealbumin of the EN group were higher than those in PN group significantly(P ＜0.05).In the eighth day after operation.the treatment group patients showed significant increase in the body weight,total protein,albumin,transferrin and prealbumin compared with those in the control group(P ＜ 0.05).On the operation morning,the transferrin and prealbmnin of EN group were increased significantly than on the fifth day before operation(P ＜ 0.01).Conclusion The preoperative and postoperative enteral nutritional support can improve the nutritlonal condition in the gastric cancer patients with nutritional risk.The preoperative enteral nutritional support can improve the patients' nutritlonal condition and reserves before operation,and reduce adverse reaction of enteral nutrition.