中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
21期
3236-3238
,共3页
廖鑑能%陈健%林志萍%李满连
廖鑑能%陳健%林誌萍%李滿連
료감능%진건%림지평%리만련
肺疾病,慢性阻塞性%呼吸衰竭%通气机,机械
肺疾病,慢性阻塞性%呼吸衰竭%通氣機,機械
폐질병,만성조새성%호흡쇠갈%통기궤,궤계
Pulmonary disease,chronic obstructive%Respiratory failure%Ventilators,mechanical
目的 观察无创通气(NIPPV)治疗急性加重期慢性阻塞性肺疾病(AECOPD)的临床效果.方法 将68例AECOPD合并Ⅱ型呼吸衰竭患者按数字表法随机分为两组:对照组予常规治疗,治疗组在常规治疗的基础上加用无创通气(BiPAP)治疗,比较两组血气分析(pH值、PaO2、PaCO2)、心率、呼吸频率,出院时统计患者住院时间、插管率及病死率.结果 两组治疗前均有CO2潴留、低氧血症、pH值下降,差异无统计学意义(均P >0.05);治疗后治疗组血气分析(pH值、PaO2、PaCO2)及呼吸频率、心率改善均较对照组明显,差异有统计学意义(均P<0.05);观察组住院时间明显短于对照组(P<0.05);插管率明显低于对照组(P<0.05),观察组病死率稍低于对照组,但差异无统计学意义(P>0.05).结论 NIPPV治疗AECOPD能够明显改善血气分析指标、降低插管率、缩短住院时间.
目的 觀察無創通氣(NIPPV)治療急性加重期慢性阻塞性肺疾病(AECOPD)的臨床效果.方法 將68例AECOPD閤併Ⅱ型呼吸衰竭患者按數字錶法隨機分為兩組:對照組予常規治療,治療組在常規治療的基礎上加用無創通氣(BiPAP)治療,比較兩組血氣分析(pH值、PaO2、PaCO2)、心率、呼吸頻率,齣院時統計患者住院時間、插管率及病死率.結果 兩組治療前均有CO2潴留、低氧血癥、pH值下降,差異無統計學意義(均P >0.05);治療後治療組血氣分析(pH值、PaO2、PaCO2)及呼吸頻率、心率改善均較對照組明顯,差異有統計學意義(均P<0.05);觀察組住院時間明顯短于對照組(P<0.05);插管率明顯低于對照組(P<0.05),觀察組病死率稍低于對照組,但差異無統計學意義(P>0.05).結論 NIPPV治療AECOPD能夠明顯改善血氣分析指標、降低插管率、縮短住院時間.
목적 관찰무창통기(NIPPV)치료급성가중기만성조새성폐질병(AECOPD)적림상효과.방법 장68례AECOPD합병Ⅱ형호흡쇠갈환자안수자표법수궤분위량조:대조조여상규치료,치료조재상규치료적기출상가용무창통기(BiPAP)치료,비교량조혈기분석(pH치、PaO2、PaCO2)、심솔、호흡빈솔,출원시통계환자주원시간、삽관솔급병사솔.결과 량조치료전균유CO2저류、저양혈증、pH치하강,차이무통계학의의(균P >0.05);치료후치료조혈기분석(pH치、PaO2、PaCO2)급호흡빈솔、심솔개선균교대조조명현,차이유통계학의의(균P<0.05);관찰조주원시간명현단우대조조(P<0.05);삽관솔명현저우대조조(P<0.05),관찰조병사솔초저우대조조,단차이무통계학의의(P>0.05).결론 NIPPV치료AECOPD능구명현개선혈기분석지표、강저삽관솔、축단주원시간.
Objective To investigate the therapeutic effect of non-invasive positi e pressure ventilation (NIPPV) in the treatment of patients with acute exacerbations of chronic obstructive pulmonary disease(AECOPD).Methods 68 AECOPD patients with type Ⅱ repiratory failure were randomly divided into control group and treatment group.The control group was treated by conventional therapy alone and the treatment group was given conventional therapy combined with NIPPV.The levels of power of hydrogen (pH),partial pressure of carbon dioxide in artery(PaCO2),arterial oxygen tension(PaO2),heart rate and repiratory rate were compared between the two groups.The mean length of patient stay,the frequency of tracheal intubation and the hospital mortality were analyzed after discharge from the hospital.Results Before treatment,the arterial blood gas analysis showed that the pH,PaCO2 and PaO2 had no significant differences between the two groups(all P > 0.05).After treatment,compared with the control group,the levels of pH,PaCO2 and PaO2 were obviously improved(all P <0.05).The mean length of patients stay in the treatment group was significantly shorter than the control group(P < 0.05).The frequency of tracheal intubation of the treatment group was significantly lower than the control group(P < 0.05).The hospital mortality was lower in the treatment group,but the difference between the two groups was not significant (P > 0.05).Conclusion NIPPV for treating the AECOPD can improve the arterial blood gas analysis,decrease the need of tracheal intubation and shorten hospitalization time.