中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
21期
3265-3266
,共2页
消化性溃疡%螺杆菌,幽门%艾普拉唑%奥美拉唑
消化性潰瘍%螺桿菌,幽門%艾普拉唑%奧美拉唑
소화성궤양%라간균,유문%애보랍서%오미랍서
Peptic ulcer%Pylori and helicobacter pylori%Ilaprazole%Omeprazole
目的 观察艾普拉唑治疗消化性溃疡的临床疗效.方法 100例消化性溃疡患者随机分为奥美拉唑组及艾普拉唑组各50例,分别予奥美拉唑、艾普拉唑治疗联合阿莫西林及克拉霉素治疗,对比两组治疗效果及临床症状缓解满意率等.结果 治疗后胃镜下表现:艾普拉唑组痊愈20例、愈合16例、有效9例、无效5例,奥美拉唑组分别为14例、12例、12例、12例,两组胃镜下治疗效果差异有统计学意义(U=3.78,P＜0.05).艾普拉唑组幽门螺杆菌清除率、临床症状缓解满意率均明显高于奥美拉唑组(x2=3.84、4.57,均P＜0.05).结论 艾普拉唑治疗消化性溃疡可获得较高的临床症状缓解满意率和幽门螺杆菌清除率.
目的 觀察艾普拉唑治療消化性潰瘍的臨床療效.方法 100例消化性潰瘍患者隨機分為奧美拉唑組及艾普拉唑組各50例,分彆予奧美拉唑、艾普拉唑治療聯閤阿莫西林及剋拉黴素治療,對比兩組治療效果及臨床癥狀緩解滿意率等.結果 治療後胃鏡下錶現:艾普拉唑組痊愈20例、愈閤16例、有效9例、無效5例,奧美拉唑組分彆為14例、12例、12例、12例,兩組胃鏡下治療效果差異有統計學意義(U=3.78,P＜0.05).艾普拉唑組幽門螺桿菌清除率、臨床癥狀緩解滿意率均明顯高于奧美拉唑組(x2=3.84、4.57,均P＜0.05).結論 艾普拉唑治療消化性潰瘍可穫得較高的臨床癥狀緩解滿意率和幽門螺桿菌清除率.
목적 관찰애보랍서치료소화성궤양적림상료효.방법 100례소화성궤양환자수궤분위오미랍서조급애보랍서조각50례,분별여오미랍서、애보랍서치료연합아막서림급극랍매소치료,대비량조치료효과급림상증상완해만의솔등.결과 치료후위경하표현:애보랍서조전유20례、유합16례、유효9례、무효5례,오미랍서조분별위14례、12례、12례、12례,량조위경하치료효과차이유통계학의의(U=3.78,P＜0.05).애보랍서조유문라간균청제솔、림상증상완해만의솔균명현고우오미랍서조(x2=3.84、4.57,균P＜0.05).결론 애보랍서치료소화성궤양가획득교고적림상증상완해만의솔화유문라간균청제솔.
Objective To observe the clinical effect of ilaprazole in the treatment of peptic ulcer.Methods 100 patients with peptic ulcer were randomly divided into omeprazole group and ilaprazole group,50 cases in each group.The patients were given omeprazole or ilaprazole combined with amoxicillin and clarithromycin.The treatment effects and clinical symptom relief satisfaction rate were compared between the two groups.Results After treatment,the results under gastroscopy:in ilaprazole group,20 cases cured,16 cases healed,9 cases were effective and 5 cases were invalid.Those in omeprazole group were 14 cases,12 cases,12 cases,12 cases respectively.The differences between the two groups were statistically significant(U =3.78,P ＜ 0.05).The removal rate of Helicobacter pylori and clinical symptom relief satisfaction rate of ilaprazole group were significantly higher than those of the omeprazole group(x2 =3.84,4.57,P ＜ 0.05).Conclusion Ilaprazole can obtain good clinical effect in treatment of peptic ulcer,with high symptom relief satisfaction rate and clearance of Helicobacter pylori.
