中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2014年
13期
1972-1973
,共2页
胎儿宫内发育迟缓%瘦素%胰岛素样生长因子-1%脂联素
胎兒宮內髮育遲緩%瘦素%胰島素樣生長因子-1%脂聯素
태인궁내발육지완%수소%이도소양생장인자-1%지련소
Intrauterine growth retardation%Leptin%Insulin-like growth factor-1%Adiponectin
目的 分析胎儿宫内发育迟缓与胎儿脐血瘦素、胰岛素样生长因子-1和脂联素的相关性.方法 61例宫内发育迟缓的胎儿作为观察组,80例发育正常胎儿作为对照组,测定两组胎儿脐血的瘦素、胰岛素样生长因子-1(IGF-1)和脂联素.结果 观察组发育迟缓胎儿脐血瘦素、胰岛素样生长因子-1、脂联素水平均明显低于对照组(t=11.239、11.680、13.640,均P＜0.01).相关分析显示出生体质量与脐血中瘦素、IGF-1和脂联素水平呈正相关(r=0.274、0.532、0.539,均P＜0.05).结论 胎儿脐血瘦素、胰岛素样生长因子-1和脂联素与宫内发育迟缓有密切关系.
目的 分析胎兒宮內髮育遲緩與胎兒臍血瘦素、胰島素樣生長因子-1和脂聯素的相關性.方法 61例宮內髮育遲緩的胎兒作為觀察組,80例髮育正常胎兒作為對照組,測定兩組胎兒臍血的瘦素、胰島素樣生長因子-1(IGF-1)和脂聯素.結果 觀察組髮育遲緩胎兒臍血瘦素、胰島素樣生長因子-1、脂聯素水平均明顯低于對照組(t=11.239、11.680、13.640,均P＜0.01).相關分析顯示齣生體質量與臍血中瘦素、IGF-1和脂聯素水平呈正相關(r=0.274、0.532、0.539,均P＜0.05).結論 胎兒臍血瘦素、胰島素樣生長因子-1和脂聯素與宮內髮育遲緩有密切關繫.
목적 분석태인궁내발육지완여태인제혈수소、이도소양생장인자-1화지련소적상관성.방법 61례궁내발육지완적태인작위관찰조,80례발육정상태인작위대조조,측정량조태인제혈적수소、이도소양생장인자-1(IGF-1)화지련소.결과 관찰조발육지완태인제혈수소、이도소양생장인자-1、지련소수평균명현저우대조조(t=11.239、11.680、13.640,균P＜0.01).상관분석현시출생체질량여제혈중수소、IGF-1화지련소수평정정상관(r=0.274、0.532、0.539,균P＜0.05).결론 태인제혈수소、이도소양생장인자-1화지련소여궁내발육지완유밀절관계.
Objective To study the correlation of leptin,insulin-like growth factor-1 (IGF-1) and adiponectin in fetal cord blood with intrauterine growth retardation (IUGR).Methods Sixty-one fetus with IUGR were enrolled into the observation group and eighty healty fetus were enrolled into the control group.Leptin,IGF-1 and adiponectin were detected.Results The levels of leptin,IGF-1 and adiponectin in the observation group were lower than those in the control group,there were significant differences between the two groups (t =11.239,11.680,13.640,all P ＜ 0.01).The body mass in the observation group was (2 157 ± 243) g,which had significantly positive correlation with leptin (r =0.274,P ＜ 0.05),IGF-1 (r =0.532,P ＜ 0.05) and adiponectin (r =0.539,P ＜ 0.05).Conclusion There was a close relationship in leptin,IGF-1 and adiponectin with IUGR.
