中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2014年
18期
2783-2785
,共3页
血府逐瘀汤%美托洛尔%冠心病%心绞痛
血府逐瘀湯%美託洛爾%冠心病%心絞痛
혈부축어탕%미탁락이%관심병%심교통
Xuefu Zhuyu Decoction%metoprolol%coronary heart disease%angina pectoris
目的 探讨血府逐瘀汤联合美托洛尔治疗老年人冠心病心绞痛的疗效及对患者血浆同型半胱氨酸和血脂水平的影响.方法 80例老年冠心病心绞痛患者,按随机数字表法分为两组各40例,研究组使用血府逐瘀汤联合美托洛尔进行治疗,对照组采用西药常规治疗,比较两组患者临床疗效及治疗前后血浆同型半胱氨酸(HCY)、血脂水平变化.结果 研究组患者治疗有效率为92.5％,明显高于对照组的65％(x2=4.58,P＜0.05);研究组治疗后血浆HCY为(15.8±3.7)μmol/L,低于对照组的(26.5±10.3) μmol/L(t=6.18,P＜0.05);研究组患者经治疗后血清中LDL、HDL、TC、TG水平较干预治疗前均明显改善(t=9.82、7.66、7.89、6.54,均P＜0.05),且改善程度较对照组明显(t=8.35、7.67、7.82、6.33,均P＜0.05).结论 血府逐瘀汤联合美托洛尔治疗老年人冠心病心绞痛疗效明显优于单纯西药治疗,值得临床推广应用.
目的 探討血府逐瘀湯聯閤美託洛爾治療老年人冠心病心絞痛的療效及對患者血漿同型半胱氨痠和血脂水平的影響.方法 80例老年冠心病心絞痛患者,按隨機數字錶法分為兩組各40例,研究組使用血府逐瘀湯聯閤美託洛爾進行治療,對照組採用西藥常規治療,比較兩組患者臨床療效及治療前後血漿同型半胱氨痠(HCY)、血脂水平變化.結果 研究組患者治療有效率為92.5％,明顯高于對照組的65％(x2=4.58,P＜0.05);研究組治療後血漿HCY為(15.8±3.7)μmol/L,低于對照組的(26.5±10.3) μmol/L(t=6.18,P＜0.05);研究組患者經治療後血清中LDL、HDL、TC、TG水平較榦預治療前均明顯改善(t=9.82、7.66、7.89、6.54,均P＜0.05),且改善程度較對照組明顯(t=8.35、7.67、7.82、6.33,均P＜0.05).結論 血府逐瘀湯聯閤美託洛爾治療老年人冠心病心絞痛療效明顯優于單純西藥治療,值得臨床推廣應用.
목적 탐토혈부축어탕연합미탁락이치료노년인관심병심교통적료효급대환자혈장동형반광안산화혈지수평적영향.방법 80례노년관심병심교통환자,안수궤수자표법분위량조각40례,연구조사용혈부축어탕연합미탁락이진행치료,대조조채용서약상규치료,비교량조환자림상료효급치료전후혈장동형반광안산(HCY)、혈지수평변화.결과 연구조환자치료유효솔위92.5％,명현고우대조조적65％(x2=4.58,P＜0.05);연구조치료후혈장HCY위(15.8±3.7)μmol/L,저우대조조적(26.5±10.3) μmol/L(t=6.18,P＜0.05);연구조환자경치료후혈청중LDL、HDL、TC、TG수평교간예치료전균명현개선(t=9.82、7.66、7.89、6.54,균P＜0.05),차개선정도교대조조명현(t=8.35、7.67、7.82、6.33,균P＜0.05).결론 혈부축어탕연합미탁락이치료노년인관심병심교통료효명현우우단순서약치료,치득림상추엄응용.
Objective To observe the effect of Xuefu Zhuyu Decoction combined with metoprolol in the treatment of senile coronary heart disease and angina pectoris and its influence on the level of blood lipid and HCY in plasma.Methods 80 cases of elderly patients with coronary heart disease and angina were randomly divided into the two groups of 40 cases according to the random number table method.The study group was treated with Xuefu Zhuyu Decoction combined with metoprolol,while the control group only used conventional western medicine for treatment,the efficacy and changes of plasma homocysteine (HCY) and serum lipid levels before and after treatment of two groups were compared.Results The effective rate of patients in the study group was 92.5 ％,significantly higher than 65％ of the control group (x2 =4.58,P ＜0.05) ;The plasma HCY of the study group after treatment was (15.8 ±3.7) μmol/L,significantly lower than (26.5 ± 10.3) μmol/L of the control group (t =6.18,P ＜0.05) ;The levels of serum LDL,TC,TG and HDL of the study group after treatment were significantly improved than before treatment (t =9.82,7.66,7.89,6.54,all P ＜ 0.05),and it improved significantly than that of the control group (t =8.35,7.67,7.82,6.33,all P ＜ 0.05).Conclusion Xuefu Zhuyu Decoction combined with metoprolol has a better effect than the pure western medicine in treatment of senile coronary heart disease and angina pectoris,which is worthy of clinical application.
