中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2014年
1期
8-10
,共3页
王陆荣%周涛%刘婷芝%成小英
王陸榮%週濤%劉婷芝%成小英
왕륙영%주도%류정지%성소영
同型半胱氨酸%高敏C反应蛋白%心血管疾病%冠心病
同型半胱氨痠%高敏C反應蛋白%心血管疾病%冠心病
동형반광안산%고민C반응단백%심혈관질병%관심병
Homocysteine%High-sensitivity C-reactive protein%Cardiovascular disease%Coronary disease
目的 探讨血清同型半胱氨酸(HCY)和高敏C反应蛋白(hs-CRP)在心血管疾病(CVD)诊疗中的临床价值.方法 通过临床试验,检测210例CVD患者和190名健康人群中血清HCY浓度,同时检测hs-CRP,进行对比分析.结果 CVD患者组(试验组)的血清HCY浓度主要集中在10～20 μ mol/L,而健康体检者(对照组)则为0～5μmol/L;试验组的血清hs-CRP浓度主要集中在2～15 mg/L,而对照组则为0～8 mg/L;试验组HCY浓度平均值为19.6μmol/L,明显高于对照组的9.4μmol/L,而试验组hs-CRP浓度平均值为8.4 mg/L,也明显高于对照组的1.3 mg/L,两组在血清HCY和hs-CRP这两项指标上存在高度一致性,且数据集中趋势比较明显.结论 综合监测血清中HCY和hs-CRP浓度的变化,对心血管疾病诊疗有十分重要的临床价值.
目的 探討血清同型半胱氨痠(HCY)和高敏C反應蛋白(hs-CRP)在心血管疾病(CVD)診療中的臨床價值.方法 通過臨床試驗,檢測210例CVD患者和190名健康人群中血清HCY濃度,同時檢測hs-CRP,進行對比分析.結果 CVD患者組(試驗組)的血清HCY濃度主要集中在10～20 μ mol/L,而健康體檢者(對照組)則為0～5μmol/L;試驗組的血清hs-CRP濃度主要集中在2～15 mg/L,而對照組則為0～8 mg/L;試驗組HCY濃度平均值為19.6μmol/L,明顯高于對照組的9.4μmol/L,而試驗組hs-CRP濃度平均值為8.4 mg/L,也明顯高于對照組的1.3 mg/L,兩組在血清HCY和hs-CRP這兩項指標上存在高度一緻性,且數據集中趨勢比較明顯.結論 綜閤鑑測血清中HCY和hs-CRP濃度的變化,對心血管疾病診療有十分重要的臨床價值.
목적 탐토혈청동형반광안산(HCY)화고민C반응단백(hs-CRP)재심혈관질병(CVD)진료중적림상개치.방법 통과림상시험,검측210례CVD환자화190명건강인군중혈청HCY농도,동시검측hs-CRP,진행대비분석.결과 CVD환자조(시험조)적혈청HCY농도주요집중재10～20 μ mol/L,이건강체검자(대조조)칙위0～5μmol/L;시험조적혈청hs-CRP농도주요집중재2～15 mg/L,이대조조칙위0～8 mg/L;시험조HCY농도평균치위19.6μmol/L,명현고우대조조적9.4μmol/L,이시험조hs-CRP농도평균치위8.4 mg/L,야명현고우대조조적1.3 mg/L,량조재혈청HCY화hs-CRP저량항지표상존재고도일치성,차수거집중추세비교명현.결론 종합감측혈청중HCY화hs-CRP농도적변화,대심혈관질병진료유십분중요적림상개치.
Objective Discuss the clinical value of serum homocysteine (HCY) and highsensitivity C-reactive protein (hs-CRP) in the diagnosis and treatment of cardiovascular disease (CVD).Methods Through the clinical test,the serum HCY concentration and hs-CRP concentration of 210 cases of CVD patients and 190 cases of healthy peoples were tested and compared.Results For serum HCY,the CVD patient group (experimental group) concentrate mainly on the range of 10-20 μ mol/L,and healthy group (control group) concentrate mainly on the range of 0-5 μ mol/L,for serum hs-CRP,the concentration of the experimental group concentrate mainly on the range of 2-15 mg/L,while the concentration of the control group concentrate mainly on the range of 0-8 mg/L,the average concentration of experimental group HCY is 19.6 μ mol/L,significantly higher than 9.4 μ mol/L of control group;the average concentration of experimental group hs-CRP is 8.4 mg/L,significantly higher than 1.3 mg/L of control group,there is a high degree of consistency in serum HCY and hs-CRP of two groups,and the central tendency of the data is more obvious.Conclusion Through comprehensive monitoring of serum HCY and hs-CRP concentration,it has important clinical value for the diagnosis and treatment of cardiovascular disease.
