CAJ | 학술논문

目的探讨乳腺癌化疗患者外周置人中心静脉导管(PICC)相关上肢静脉血栓形成的临床诊疗.方法回顾性分析北京协和医院201 1至2012年938例乳腺癌化疗患者中,PICC相关有症状上肢静脉血栓形成的发生率、诊断和治疗.结果 10例乳腺癌患者出现PICC相关有症状上肢静脉血栓,发生率为1.1％ (10/938),每1000个导管留置日中的血栓例数为0.11,共携带导管1035 d,置管后血栓发生中位时间23.5 (4～176)d,9例患者采用低分子肝素抗凝,中位抗凝时间为14(3 ～50)d,5例患者抗凝后继续使用导管,所有患者均无肺栓塞发生.结论 PICC相关上肢静脉血栓形成在乳腺癌化疗患者中发生率低,早期诊断及治疗后,仍可取得较好的临床结局.
목적 탐토유선암화료환자외주치인중심정맥도관(PICC)상관상지정맥혈전형성적림상진료.방법 회고성분석북경협화의원201 1지2012년938례유선암화료환자중,PICC상관유증상상지정맥혈전형성적발생솔、진단화치료.결과 10례유선암환자출현PICC상관유증상상지정맥혈전,발생솔위1.1％ (10/938),매1000개도관류치일중적혈전례수위0.11,공휴대도관1035 d,치관후혈전발생중위시간23.5 (4～176)d,9례환자채용저분자간소항응,중위항응시간위14(3 ～50)d,5례환자항응후계속사용도관,소유환자균무폐전새발생.결론 PICC상관상지정맥혈전형성재유선암화료환자중발생솔저,조기진단급치료후,잉가취득교호적림상결국.
Objective To summarize our experiences in the diagnosis and treatment of peripherally inserted central venous catheter (PICC)-associated symptomatic upper extremity vein thrombosis (UEVT) in breast cancer patients undergoing chemotherapy.Methods A retrospective study of 938 breast cancer patients with PICC from 2011 to 2012 in Peking Union Medical College Hospital were performed.The diagnosis and treatment of PICC-related symptomatic UEVT was analyzed.Results Ten patients (1.1％) developed PICCassociated symptomatic UEVT in 23.5 (4 ～ 176) days after catheter placement,for a total of 1035 catheterdays,with an incidence of 0.11 per 1000 catheter-days.Nine patients were treated with low-molecular-weight heparin for 14 (3 ～50) days,and 5 of them used catheter during anticoagulant therapy without PICC removal.No pulmonary embolus was noted in any patient.Conclusions The incidence of PICC-associated symptomatic UEVT is relatively low.Early diagnosis and treatment can achieve a good clinical outcome in these patients.