中华临床营养杂志
中華臨床營養雜誌
중화림상영양잡지
CHINESE JOURNAL OF CLINICAL NUTRITION
2014年
3期
141-144
,共4页
水解乳清蛋白%婴儿配方%食物过敏%婴儿湿疹
水解乳清蛋白%嬰兒配方%食物過敏%嬰兒濕疹
수해유청단백%영인배방%식물과민%영인습진
Whey protein hydrolyzed%Infant formula%Food allergy%Infantile eczema
目的 探讨深度水解乳清蛋白配方奶及适度水解乳清蛋白配方奶作为婴儿湿疹辅助治疗措施的临床价值.方法 将59例人工喂养患有婴儿湿疹的足月儿按喂养配方不同分为深度水解乳清蛋白配方组(eHF组,n=18)、适度水解乳清蛋白配方组(pHF组,n=22)及普通牛奶配方组(CMF组,n=19),在外用药物治疗相同的情况下,利用特应性皮炎积分指数观察治疗的有效率、缓解率等.结果 治疗2周后eHF组治疗有效率38.9％及缓解率50.0％,与CMF组的5.3％及31.6％相比差异有统计学意义(x2 =12.225,P=0.002);pHF组治疗有效率9.1％及缓解率40.9％,与CMF组相比差异无统计学意义(x2 =0.761,P=0.683).治疗8周后,eHF组治疗有效率55.6％及缓解率38.9％,与CMF组的15.8％及47.4％相比差异有统计学意义(x2=8.498,P=0.014);pHF组治疗有效率31.8％及缓解率59.1％有高于CMF组的趋势,但差异无统计学意义(x2 =4.912,P=0.086).治疗前(F =0.773,P=0.466)、后(F=1.313,P=0.277)小儿生长发育指标各组间差异无统计学意义.结论 深度水解乳清蛋白配方及适度水解乳清蛋白配方奶均可辅助治疗婴儿湿疹,但深度水解配方治疗显效较快.
目的 探討深度水解乳清蛋白配方奶及適度水解乳清蛋白配方奶作為嬰兒濕疹輔助治療措施的臨床價值.方法 將59例人工餵養患有嬰兒濕疹的足月兒按餵養配方不同分為深度水解乳清蛋白配方組(eHF組,n=18)、適度水解乳清蛋白配方組(pHF組,n=22)及普通牛奶配方組(CMF組,n=19),在外用藥物治療相同的情況下,利用特應性皮炎積分指數觀察治療的有效率、緩解率等.結果 治療2週後eHF組治療有效率38.9％及緩解率50.0％,與CMF組的5.3％及31.6％相比差異有統計學意義(x2 =12.225,P=0.002);pHF組治療有效率9.1％及緩解率40.9％,與CMF組相比差異無統計學意義(x2 =0.761,P=0.683).治療8週後,eHF組治療有效率55.6％及緩解率38.9％,與CMF組的15.8％及47.4％相比差異有統計學意義(x2=8.498,P=0.014);pHF組治療有效率31.8％及緩解率59.1％有高于CMF組的趨勢,但差異無統計學意義(x2 =4.912,P=0.086).治療前(F =0.773,P=0.466)、後(F=1.313,P=0.277)小兒生長髮育指標各組間差異無統計學意義.結論 深度水解乳清蛋白配方及適度水解乳清蛋白配方奶均可輔助治療嬰兒濕疹,但深度水解配方治療顯效較快.
목적 탐토심도수해유청단백배방내급괄도수해유청단백배방내작위영인습진보조치료조시적림상개치.방법 장59례인공위양환유영인습진적족월인안위양배방불동분위심도수해유청단백배방조(eHF조,n=18)、괄도수해유청단백배방조(pHF조,n=22)급보통우내배방조(CMF조,n=19),재외용약물치료상동적정황하,이용특응성피염적분지수관찰치료적유효솔、완해솔등.결과 치료2주후eHF조치료유효솔38.9％급완해솔50.0％,여CMF조적5.3％급31.6％상비차이유통계학의의(x2 =12.225,P=0.002);pHF조치료유효솔9.1％급완해솔40.9％,여CMF조상비차이무통계학의의(x2 =0.761,P=0.683).치료8주후,eHF조치료유효솔55.6％급완해솔38.9％,여CMF조적15.8％급47.4％상비차이유통계학의의(x2=8.498,P=0.014);pHF조치료유효솔31.8％급완해솔59.1％유고우CMF조적추세,단차이무통계학의의(x2 =4.912,P=0.086).치료전(F =0.773,P=0.466)、후(F=1.313,P=0.277)소인생장발육지표각조간차이무통계학의의.결론 심도수해유청단백배방급괄도수해유청단백배방내균가보조치료영인습진,단심도수해배방치료현효교쾌.
Objective To study the clinical value of extensively whey protein hydrolyzed formula and partially whey protein hydrolyzed formula as an adjunctive therapy in treating infantile eczema.Methods Totally 59 bottle-feeding babies with infantile eczema were divided into three groups depending on different formula feeding:extensively hydrolyzed formula feeding group (eHF group,n =18),partially hydrolyzed formula feeding group (pHF group,n =22),and conventional cow's milk formula feeding group (CMF group,n =19).Meanwhile,all patients received the same drug treatment.The effective rate and remission rate were evaluated using the SCORing Atopic Dermatitis (SCORAD) index.Results After 2 weeks of treatment,the effective rate was 38.9％ and the remission rate was 50.0％ in the eHF group,which were significantly different from those in the CMF group (5.3％ and 31.6％) (x2 =12.225,P =0.002).The effective rate was 9.1％ and the remission rate was 40.9％ in the pHF group,showing no significant difference when compared with the CMF group (x2 =0.761,P =0.683).After 8 weeks of treatment,the effective rate was 55.6％ and the remission rate was 38.9％ in the eHF group,comparing to 15.8％ and 47.4％ in the CMF group,the difference was statistically significant (x2 =8.498,P =0.014).The effective rate was 31.8 ％ and the remission rate was 59.1％ in the pHF group,a trend towards higher than that of the CMF group,but the difference was not statistically significant (x2 =4.912,P =0.086).Before (F =0.773,P =0.466) and after (F =1.313,P =0.277) the treatment,the growth and development data in different groups showed no significance differences.Conclusion Both the extensively and partially whey protein hydrolyzed formula play an adjunctive role in treating infantile eczema,although the treatment effectiveness of the extensively hydrolyzed formula appears earlier than that of the partially hydrolyzed formula.
