中华临床营养杂志
中華臨床營養雜誌
중화림상영양잡지
CHINESE JOURNAL OF CLINICAL NUTRITION
2014年
5期
267-272
,共6页
中链甘油三酯%营养干预%指征%现状%评价
中鏈甘油三酯%營養榦預%指徵%現狀%評價
중련감유삼지%영양간예%지정%현상%평개
Medium-chain triglycerides%Nutritional intervention%Indication%Current status%Evaluation
目的 调查中链甘油三酯(MCT)膳食及其医用食品在住院患者中的应用现状,结合文献证据评价其使用指征,阐明其临床应用的合理指征把握和临床地位.方法 分析北京协和医院2012年1月至2013年12月46例次应用MCT进行膳食营养干预的住院患者情况.结果 MCT医用食品的膳食营养干预在临床实践中尚未广泛应用,但使用例次呈上升趋势,涉及消化科、儿科,呼吸科、普通内科、基本外科等13类病房.37.0％的患者存在营养不良,56.5％的患者存在低白蛋白血症.MCT干预的主要指征包括胃肠功能障碍(21例)与淋巴循环障碍(15例),此外,血脂异常(5例)、胰腺外分泌功能不全(4例)以及难治性癫痫发作(1例)的患者也进行了MCT的营养干预.结论 目前应用MCT干预的基本临床指征与文献证据基本一致,但其目前研究证据及临床应用依然有限,期待更多高质量的大样本临床研究,指导并规范合理的营养干预.
目的 調查中鏈甘油三酯(MCT)膳食及其醫用食品在住院患者中的應用現狀,結閤文獻證據評價其使用指徵,闡明其臨床應用的閤理指徵把握和臨床地位.方法 分析北京協和醫院2012年1月至2013年12月46例次應用MCT進行膳食營養榦預的住院患者情況.結果 MCT醫用食品的膳食營養榦預在臨床實踐中尚未廣汎應用,但使用例次呈上升趨勢,涉及消化科、兒科,呼吸科、普通內科、基本外科等13類病房.37.0％的患者存在營養不良,56.5％的患者存在低白蛋白血癥.MCT榦預的主要指徵包括胃腸功能障礙(21例)與淋巴循環障礙(15例),此外,血脂異常(5例)、胰腺外分泌功能不全(4例)以及難治性癲癇髮作(1例)的患者也進行瞭MCT的營養榦預.結論 目前應用MCT榦預的基本臨床指徵與文獻證據基本一緻,但其目前研究證據及臨床應用依然有限,期待更多高質量的大樣本臨床研究,指導併規範閤理的營養榦預.
목적 조사중련감유삼지(MCT)선식급기의용식품재주원환자중적응용현상,결합문헌증거평개기사용지정,천명기림상응용적합리지정파악화림상지위.방법 분석북경협화의원2012년1월지2013년12월46례차응용MCT진행선식영양간예적주원환자정황.결과 MCT의용식품적선식영양간예재림상실천중상미엄범응용,단사용례차정상승추세,섭급소화과、인과,호흡과、보통내과、기본외과등13류병방.37.0％적환자존재영양불량,56.5％적환자존재저백단백혈증.MCT간예적주요지정포괄위장공능장애(21례)여림파순배장애(15례),차외,혈지이상(5례)、이선외분비공능불전(4례)이급난치성전간발작(1례)적환자야진행료MCT적영양간예.결론 목전응용MCT간예적기본림상지정여문헌증거기본일치,단기목전연구증거급림상응용의연유한,기대경다고질량적대양본림상연구,지도병규범합리적영양간예.
Objective To analyze the current dietary application of medium-chain triglycerides (MCT) in hospitalized patients,and clarify the appropriate indications and the role of MCT in clinical practice through evidence-based evaluation.Method A retrospective analysis was conducted on 46 cases of hospitalized patients who were administered dietary MCT between January,2012 and December,2013 in Peking Union Medical College Hospital.Results Dietary MCT were utilized in a small but increasing number of patients,who distributed in departments of gastroenterology,pediatrics,pneumology,general internal medicine,and general surgery.37.0％ of the patients had malnutrition,while 56.5％ had hypoalbuminemia.The leading indications of MCT therapy were gastrointestinal dysfunction (21 cases) and lymph circulation disorder (15 cases),while dyslipidemia (5 cases),exocrine pancreatic insufficiency (4 cases),and intractable epilepsy (1 case) served as other indications of MCT administration.Conclusions The indications of current dietary MCT application are approximately consistent with evidence from literature.However,given the scarcity of relevant researches and limited clinical application,further clinical researches with larger samples on dietary MCT are needed to provide more high-quality evidences for guidance of clinical practice.
