中华临床营养杂志
中華臨床營養雜誌
중화림상영양잡지
CHINESE JOURNAL OF CLINICAL NUTRITION
2014年
5期
285-287
,共3页
李军%刘菁%武美艳%车超%鞠秀丽%李保敏
李軍%劉菁%武美豔%車超%鞠秀麗%李保敏
리군%류정%무미염%차초%국수려%리보민
癫痫%维生素B1%维生素B6%维生素B12
癲癇%維生素B1%維生素B6%維生素B12
전간%유생소B1%유생소B6%유생소B12
Epilepsy%Vitamin B1%Vitamin B6%Vitamin B12
目的 探讨B族维生素(B1、B6、B12)与癫痫发生的相关性.方法 选取2013年1至10月新诊断的癫痫患儿(均未服用抗癫痫药物)与非癫痫患儿各50例,应用LK3000V维生素检测仪分别检测各组血清B族维生素(B1、B6、B12)浓度.结果 癫痫患儿血清中维生素B1和B12的浓度分别为(132.81 ±7.31) nmol/L和(221.41±26.09) pg/ml,与非癫痫患儿血清中维生素B1和B12浓度[(130.44±5.12) nmol/L和(197.87±19.36) pg/ml]相比,差异无统计学意义(P=0.095,P=0.077).癫痫患儿血清中维生素B6的浓度为(44.61 ±2.49) μmol/L,显著低于非癫痫患儿的血清维生素B6浓度(64.63±5.71) μmol/L (P=0.031).结论 血清维生素B1、B12含量与癫痫无相关性,而血清维生素B6含量低下可能增加癫痫发作的风险.
目的 探討B族維生素(B1、B6、B12)與癲癇髮生的相關性.方法 選取2013年1至10月新診斷的癲癇患兒(均未服用抗癲癇藥物)與非癲癇患兒各50例,應用LK3000V維生素檢測儀分彆檢測各組血清B族維生素(B1、B6、B12)濃度.結果 癲癇患兒血清中維生素B1和B12的濃度分彆為(132.81 ±7.31) nmol/L和(221.41±26.09) pg/ml,與非癲癇患兒血清中維生素B1和B12濃度[(130.44±5.12) nmol/L和(197.87±19.36) pg/ml]相比,差異無統計學意義(P=0.095,P=0.077).癲癇患兒血清中維生素B6的濃度為(44.61 ±2.49) μmol/L,顯著低于非癲癇患兒的血清維生素B6濃度(64.63±5.71) μmol/L (P=0.031).結論 血清維生素B1、B12含量與癲癇無相關性,而血清維生素B6含量低下可能增加癲癇髮作的風險.
목적 탐토B족유생소(B1、B6、B12)여전간발생적상관성.방법 선취2013년1지10월신진단적전간환인(균미복용항전간약물)여비전간환인각50례,응용LK3000V유생소검측의분별검측각조혈청B족유생소(B1、B6、B12)농도.결과 전간환인혈청중유생소B1화B12적농도분별위(132.81 ±7.31) nmol/L화(221.41±26.09) pg/ml,여비전간환인혈청중유생소B1화B12농도[(130.44±5.12) nmol/L화(197.87±19.36) pg/ml]상비,차이무통계학의의(P=0.095,P=0.077).전간환인혈청중유생소B6적농도위(44.61 ±2.49) μmol/L,현저저우비전간환인적혈청유생소B6농도(64.63±5.71) μmol/L (P=0.031).결론 혈청유생소B1、B12함량여전간무상관성,이혈청유생소B6함량저하가능증가전간발작적풍험.
Objective To investigate the correlation of serum concentration of B vitamins B1,B6,B12) with the incidence of epilepsy.Methods We recruited 50 newly diagnosed patients with epilepsy (not receiving antiepileptic drugs) and 50 patients without epilepsy.Serum concentrations of B vitamins (B1,B6,and B12) in both groups were detected with a LK3000V vitamin detector.Results The concentrations of vitamin B1 and B12 in epileptic patients were (132.81 ±7.3l) nmol/L and (221.41 ±26.09) pg/ml,respectively,not significantly different from those in non-epileptic patients [(130.44 ± 5.12) nmol/L,P =0.095 ;(197.87 ± 19.36) pg/ml,P =0.077].The concentration of vitamin B6 in epileptic children was (44.61 ±2.49) μmol/L,significantly lower than that in non-epileptic children [(64.63 ± 5.71) μmol/L,P =0.031].Conclusion Though serum concentrations of vitamin B1 and B12 may not be associated with epilepsy,lower concentration of vitamin B6 in serum may increase the risk of epilepsy.
