CAJ | 학술논문

目的探讨蓝黄视野检查法(Blue on Yellow Perimetry,BYP)、自动视野检查法(stmdard Automatic Perimetry,SAP)和光学相干断层成像(Optical Coherence Tonometry,OCT)在原发性开角型青光眼诊断中的应用.方法 POAG患者42例66只眼,24例双眼、18例单眼,男性30例48只眼,女性12例18只眼,左32只眼、右36只眼,年龄为19～69岁,平均(38.06±14.86)岁.应用HUMPHERY750Ⅱ-i电脑自动视野计的Sita-Standard检测程序进行SAP检查和蓝黄视野检测程序来进行BYP检查,应用STRATUSOCTTM型OCT检查视网膜神经纤维层(RNFL)平均厚度.结果 SAP、BYP和OCT三种检测方法的阳性率分别为75.00%、93.75%和84.37%,三者总体的差异比较无统计学意义(P=0.118).POAG早期SAP和BYP的平均缺损(MD)值与OCT检测的RNFL平均厚度均存在相关关系.进展期和晚期,SAP和BYP的MD值与RNFL平均厚度则均存在相关关系和线性回归关系.进展期和晚期,BYP的MD值与RNFL平均厚度的决定系数均高于SAP.早期、进展期和晚期SAP和BYP的PSD与RNFL平均厚度均不存在相关.结论 BYP比SAP更能进一步反映POAG视野和视功能的损害程度.BYP、SAP和OCT联合应用可提高POAG早期诊断的敏感性.
목적 탐토람황시야검사법(Blue on Yellow Perimetry,BYP)、자동시야검사법(stmdard Automatic Perimetry,SAP)화광학상간단층성상(Optical Coherence Tonometry,OCT)재원발성개각형청광안진단중적응용.방법 POAG환자42례66지안,24례쌍안、18례단안,남성30례48지안,녀성12례18지안,좌32지안、우36지안,년령위19～69세,평균(38.06±14.86)세.응용HUMPHERY750Ⅱ-i전뇌자동시야계적Sita-Standard검측정서진행SAP검사화람황시야검측정서래진행BYP검사,응용STRATUSOCTTM형OCT검사시망막신경섬유층(RNFL)평균후도.결과 SAP、BYP화OCT삼충검측방법적양성솔분별위75.00%、93.75%화84.37%,삼자총체적차이비교무통계학의의(P=0.118).POAG조기SAP화BYP적평균결손(MD)치여OCT검측적RNFL평균후도균존재상관관계.진전기화만기,SAP화BYP적MD치여RNFL평균후도칙균존재상관관계화선성회귀관계.진전기화만기,BYP적MD치여RNFL평균후도적결정계수균고우SAP.조기、진전기화만기SAP화BYP적PSD여RNFL평균후도균불존재상관.결론 BYP비SAP경능진일보반영POAG시야화시공능적손해정도.BYP、SAP화OCT연합응용가제고POAG조기진단적민감성.
Objective To evaluate application of Blue-on-Yellow Perimetry(BYP),Standard Automatic Perimerty (SAP)and Optical Coherence Tomography(OCT)in the diagnosis of primary open angle glaucoma(POAG)patients.Methods A total of 42 patients(66 eyes)diagnosed POAG were enrolled for examination of SAP with sita-standard strategy and BYP with fastpac strategy by Humphrey 750 Ⅱ-Ⅰ perimetry,and the average thiekness of RNFL by StratusocTM OCT.There were 12 females(18 eyes)and 30males(48 eyes),32 left eyes,36 Right eyes.Mean(SD)age of the patients was 38.06(14.86)years(range,19-69 years).Results The positive rate of SAP,BYP and OCT was 75.00%,93.75%and 84.37%respectively,Chi-square test showed that the differences between the three groups were not statistically significant.The MD values.either SAP or BYP.had no correlation with the average thickness of RNFI in the early period of POAG.The correlation and linear regression was found in the moderate and advanced period of POAG between MD values and the average thickness of RNFL,either SAP or BYP.MD values of BYP showed a higher correlation index than SAP both in the moderate and the advanced period.There was no correlation between PSD values of SAP and BYP and the average thickness of RNFL in every period of POAG.Conclusions BYP is more sensitive than SAP in the diagnosis ofPOAG.SAP,BYP and OCT should be combined in the visual field and visual function examination to promote the diagnosis sensitivity of POAG.