中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2014年
6期
725-728
,共4页
非动脉炎性前段缺血性视神经病变%特发性视神经炎%眼灌注压%眼部血流动力学
非動脈炎性前段缺血性視神經病變%特髮性視神經炎%眼灌註壓%眼部血流動力學
비동맥염성전단결혈성시신경병변%특발성시신경염%안관주압%안부혈류동역학
Non-arteritic anterior ischemic optic neuropathy (NAION)%Idiopathic optic neuritis (ION)%Ocular perfusion pressure (OPP)%Ocular hemodynamics
目的 比较非炎性前部缺血性视神经病变(NAION)和特发性视神经炎(ION)的眼灌注压与眼部血流动力学,分析其与固视性质之间的关系.方法 回顾性病例研究.收集2011年3月至2013年5月间在中国医科大学附属第四医院眼科诊治的NAION和ION患者的病例资料,记录患者的发病年龄、性别组成、全身疾病;按固视性质分为中心视力和中心外视力,比较眼灌注压和眼部血流动力学的差异,分析造成这些差异的原因.结果 NAION患者21例21只眼(中心视力者14只眼、中心外视力者7只眼),ION患者21例21只眼(中心视力者8只眼、中心外视力者13只眼).中心视力眼中,睫状后动脉和视网膜中央动脉的收缩期峰速在NAION组明显低于ION组,差异有统计学意义(t=12.49,P=0.00;t=14.25,P=0.00);中心外视力眼中,坐位肱动脉的平均动脉压和眼灌注压NAION组明显高于ION组、睫状后动脉和视网膜中央动脉的收缩期峰速NAION组明显低于ION组,差异有统计学意义(t =6.41,P=0.02;t=5.66,P=0.03;t=8.47,P=0.01;t=11.32,P=0.00).不按固视性质分类,仍然将视力都按中心视力统计,睫状后动脉和视网膜中央动脉的收缩期峰速NAION组明显低于ION组,差异均有统计学意义(t=5.81,P=0.02;t=9.20,P=0.00).结论 NAION和ION患眼的固视性质有中心视力和中心外视力之分,比较眼灌注压、眼部血流动力学指标也要分别统计.
目的 比較非炎性前部缺血性視神經病變(NAION)和特髮性視神經炎(ION)的眼灌註壓與眼部血流動力學,分析其與固視性質之間的關繫.方法 迴顧性病例研究.收集2011年3月至2013年5月間在中國醫科大學附屬第四醫院眼科診治的NAION和ION患者的病例資料,記錄患者的髮病年齡、性彆組成、全身疾病;按固視性質分為中心視力和中心外視力,比較眼灌註壓和眼部血流動力學的差異,分析造成這些差異的原因.結果 NAION患者21例21隻眼(中心視力者14隻眼、中心外視力者7隻眼),ION患者21例21隻眼(中心視力者8隻眼、中心外視力者13隻眼).中心視力眼中,睫狀後動脈和視網膜中央動脈的收縮期峰速在NAION組明顯低于ION組,差異有統計學意義(t=12.49,P=0.00;t=14.25,P=0.00);中心外視力眼中,坐位肱動脈的平均動脈壓和眼灌註壓NAION組明顯高于ION組、睫狀後動脈和視網膜中央動脈的收縮期峰速NAION組明顯低于ION組,差異有統計學意義(t =6.41,P=0.02;t=5.66,P=0.03;t=8.47,P=0.01;t=11.32,P=0.00).不按固視性質分類,仍然將視力都按中心視力統計,睫狀後動脈和視網膜中央動脈的收縮期峰速NAION組明顯低于ION組,差異均有統計學意義(t=5.81,P=0.02;t=9.20,P=0.00).結論 NAION和ION患眼的固視性質有中心視力和中心外視力之分,比較眼灌註壓、眼部血流動力學指標也要分彆統計.
목적 비교비염성전부결혈성시신경병변(NAION)화특발성시신경염(ION)적안관주압여안부혈류동역학,분석기여고시성질지간적관계.방법 회고성병례연구.수집2011년3월지2013년5월간재중국의과대학부속제사의원안과진치적NAION화ION환자적병례자료,기록환자적발병년령、성별조성、전신질병;안고시성질분위중심시력화중심외시력,비교안관주압화안부혈류동역학적차이,분석조성저사차이적원인.결과 NAION환자21례21지안(중심시력자14지안、중심외시력자7지안),ION환자21례21지안(중심시력자8지안、중심외시력자13지안).중심시력안중,첩상후동맥화시망막중앙동맥적수축기봉속재NAION조명현저우ION조,차이유통계학의의(t=12.49,P=0.00;t=14.25,P=0.00);중심외시력안중,좌위굉동맥적평균동맥압화안관주압NAION조명현고우ION조、첩상후동맥화시망막중앙동맥적수축기봉속NAION조명현저우ION조,차이유통계학의의(t =6.41,P=0.02;t=5.66,P=0.03;t=8.47,P=0.01;t=11.32,P=0.00).불안고시성질분류,잉연장시력도안중심시력통계,첩상후동맥화시망막중앙동맥적수축기봉속NAION조명현저우ION조,차이균유통계학의의(t=5.81,P=0.02;t=9.20,P=0.00).결론 NAION화ION환안적고시성질유중심시력화중심외시력지분,비교안관주압、안부혈류동역학지표야요분별통계.
Objective To compare the Ocular perfusion pressure (OPP) and ocular hemodynamics of patients with non-arteritic anterior ischemic optic neuropathy (NAION) and idiopathic optic neuritis (ION),and analyze their relationship with fixation features.Methods It was a retrospective case study.Data were collected in patients with NAION and ION who were treated in Department of Ophthalmology,the Fourth Affiliated Hospital,China Medical University from March 2011 to May 2013.OPP and ocular hemodynamics were analyzed,as well as the ages,gender,and systemic diseases after these patients were divided as the central fixation group and the extra-central fixation one on the basis of ocular fixation features.The reason making the differences were thought over.Results There were 21 NAION cases (21 eyes,14 for central fixation and 7 for extra-central fixation) and 21 ION ones (21 eyes,8 for central fixation and 13 for extra-central fixation).The peak systolic velocity (PSV) of posterior ciliary artery (PCA) and central retinal artery (CRA) were significantly decreased in the NAION group comparing with the ION group in central fixation eyes (t =12.49,P =0.00; t =14.25,P =0.00).In the extra-central fixation eyes,the sitting mean artery pressure (MAP) of brachial artery and OPP were significantly increased in the NAION group,and the PSV of PCA and CRA were significantly decreased in the NAION group (t =6.41,P =0.02; t =5.66,P =0.03; t =8.47,P =0.01; t =11.32,P =0.00).However,the PSV of PCA and CRA were significantly decreased in the NAION group when the fixation features were excluded from the classification criteria and all kinds of vision was regarded totally as central fixation vision (t =5.81,P =0.02; t =9.20,P =0.00).Conclusions The fixation features of NAION and ION eyes can be classified as central fixation and extra-central fixation.The comparisons of OPP and ocular hemodynamics should be classified according to the fixation features.
