CAJ | 학술논문

目的探讨影响腹腔镜右半结肠癌切除术后患者生存时间的因素.方法收集并回顾性分析2004年2月至2011年3月间北京大学第三医院普通外科经腹腔镜施行右半结肠癌切除术患者的病例资料和随访资料,运用Kaplan-Meier法计算生存率并进行单因素分析,利用Cox比例风险模型进行多因素分析.结果 164例腹腔镜右半结肠癌切除术患者中,中转开腹12例(7.3％).围手术期并发症发生率为18.9％(31/164).中位随访时间为27(5～85)个月.全组5年总体生存率为81.5％,5年无瘤生存率为75.7％,5年肿瘤相关生存率为78.7％.单因素分析和多因素分析结果均显示,TNM分期及中转开腹对患者生存时间的影响有统计学意义(P＜0.05).结论 TNM分期及中转开腹是影响腹腔镜右半结肠癌切除术后患者生存时间的独立因素.
목적 탐토영향복강경우반결장암절제술후환자생존시간적인소.방법 수집병회고성분석2004년2월지2011년3월간북경대학제삼의원보통외과경복강경시행우반결장암절제술환자적병례자료화수방자료,운용Kaplan-Meier법계산생존솔병진행단인소분석,이용Cox비례풍험모형진행다인소분석.결과 164례복강경우반결장암절제술환자중,중전개복12례(7.3％).위수술기병발증발생솔위18.9％(31/164).중위수방시간위27(5～85)개월.전조5년총체생존솔위81.5％,5년무류생존솔위75.7％,5년종류상관생존솔위78.7％.단인소분석화다인소분석결과균현시,TNM분기급중전개복대환자생존시간적영향유통계학의의(P＜0.05).결론 TNM분기급중전개복시영향복강경우반결장암절제술후환자생존시간적독립인소.
Objective To evaluate factors associated with postoperative survival after laparoscopic right hemicolectomy for colon cancer.Methods Clinical data of patients undergoing laparoscopic right hemicolectomy in the Department of General Surgery,the Peking University Third Hospital from February 2004 to March 2011 were obtained and analyzed.Kaplan-Meier method was used to calculate survival rate and univariate analysis was performed.Proportional-hazards regression model(Cox model) was used for multivariate analysis.Results A total of 164 cases were included in this study.The conversion rate was 7.3％(12/164) and the postoperative morbidity was 18.9％(31/164).After a median follow-up period of 27 months (range from 5 to 85 months),the 5-year overall survival rate was 81.5％ and the 5-year disease free survival rate was 75.7％ and 5-year cancer related survival rate was 78.7％.Both univariate and multivariate analysis showed that the TNM staging and conversion were independent prognostic factors (P＜0.05).Conclusion The tumor stage and conversion are independent prognostic factors for patients undergoing the laparoscopic right hemicolectomy.