CAJ | 학술논문

全球胃癌发病率呈逐渐下降趋势,但我国人口众多,每年新发胃癌人数仍极庞大.国内多家诊疗中心已建立了胃癌多学科诊疗团队,但在外科手术、化疗、放疗乃至生物靶向治疗等具体策略方面,仍有进一步优化的空间.目前的研究热点包括:合理应用各种技术做精确的术前分期、局部进展期胃癌的围手术期化疗、微创外科技术在各期胃癌中的应用价值、临床研究与基础科研的合理转化以及胃癌的个体化治疗等.中西方胃癌的生物学行为及各类分子事件存在差异,期待有更多源自东方的临床研究证据,充实我国胃癌治疗临床实践.
전구위암발병솔정축점하강추세,단아국인구음다,매년신발위암인수잉겁방대.국내다가진료중심이건립료위암다학과진료단대,단재외과수술、화료、방료내지생물파향치료등구체책략방면,잉유진일보우화적공간.목전적연구열점포괄:합리응용각충기술주정학적술전분기、국부진전기위암적위수술기화료、미창외과기술재각기위암중적응용개치、림상연구여기출과연적합리전화이급위암적개체화치료등.중서방위암적생물학행위급각류분자사건존재차이,기대유경다원자동방적림상연구증거,충실아국위암치료림상실천.
The incidence of gastric cancer has declined worldwide in the past decades.However,due to the large number of population in mainland of China,the absolute number of newly-diagnosed patients in this developing country is still very high.Most of the major clinical centers have established multi-disciplinary team,but the strategy in treating this life-threatening disease still needs to be optimized,including the precise preoperative staging by various techniques,perioperative chemotherapy for locally advanced diseases,role of minimally invasive surgical approaches in treating patients with different stages,translational research to fill the gap between clinical trials and basic research,as well as the individualized treatment for gastric cancer.We believe that the biological behaviors and molecular events of gastric cancer in eastern countries are different from that of Western countries,so the clinical evidences derived from Eastern countries need to be strengthened to enrich the unmet demands in the clinical practice in China.