CAJ | 학술논문

目的探讨十二指肠胃肠间质瘤(GIST)的临床病理特征及外科治疗.方法回顾性分析2007年1月至2011年7月间四川大学华西医院收治的25例十二指肠GIST患者的临床资料.结果 25例患者临床上均无特异性症状,肿瘤位于十二指肠球部、降部、水平部及升部分别为2例、11例、8例和4例,极低度、低度、中度、高度危险者分别为2例、7例、6例和10例.均予以手术切除,其中11例行胰十二指肠切除,10例行十二指肠肿瘤局部切除,2例行十二指肠节段切除,2例行远端胃大部切除.18例患者随访16～39个月,期间有3例患者分别于术后18、30和35个月复发.结论十二指肠GIST临床缺乏特异性表现,手术完整切除是最主要的治疗方法.
목적 탐토십이지장위장간질류(GIST)적림상병리특정급외과치료.방법 회고성분석2007년1월지2011년7월간사천대학화서의원수치적25례십이지장GIST환자적림상자료.결과 25례환자림상상균무특이성증상,종류위우십이지장구부、강부、수평부급승부분별위2례、11례、8례화4례,겁저도、저도、중도、고도위험자분별위2례、7례、6례화10례.균여이수술절제,기중11례행이십이지장절제,10례행십이지장종류국부절제,2례행십이지장절단절제,2례행원단위대부절제.18례환자수방16～39개월,기간유3례환자분별우술후18、30화35개월복발.결론 십이지장GIST림상결핍특이성표현,수술완정절제시최주요적치료방법.
Objective To investigate the clinicopathological characteristics and surgical treatment of duodenal gastrointestinal stromal tumor (GIST).Methods Clinicopathological data of 25 cases with duodenal GIST from January 2007 to July 2011 in West China hospital were retrospectively analyzed.Results All the patients were identified by pathological examination without specific symptoms.Tumors were located in the bulb area in 2 cases,descending portion in 11 cases,transverse portion in 8 cases,and ascending portion in 4 cases.Two cases were at very low risk,7 at low risk,6 at intermediate risk,and 10 at high risk.All the patients received surgical resection,including 11 pancreaticoduodenectomies,10 local tumor resections,2 duodenal segmental resections,and 2 distal subtotal gastrectomies.Eighteen patients were followed up from 16 to 39 months and 3 patients recurred 18,30,and 35 months after operation respectively.Conclusions Duodenal GIST exhibits no distinct clinical characteristics.Complete removal of the tumor is the main choice of treatment.