CAJ | 학술논문

目的观察食管癌术后红霉素对胃电图和胃排空的影响.方法将30例食管癌切除食管胃弓上吻合术后患者分成试验组与对照组,每组各15例,分别于术前、术后1、3、6和12个月进行胃电图和放射性核素胃排空检查.试验组术后于检查前1周开始口服红霉素0.25 g/次,每日3次.结果术后患者胃电图平均振幅、主频以及正常慢波百分比较术前均降低,术后1个月,试验组各参数均已达到术前水平,而对照组术后1年才达到术前水平(P＞0.05).术后患者胃排空明显延缓,术后12个月试验组半量胃排空时间达到术前水平(P＞0.05),而对照组远未达到术前正常水平(P＜0.01).结论红霉素促进食管癌术后胃电活动和胃排空功能的恢复.胃排空恢复迟于胃电活动的恢复可能与胃壁的缺血、水肿有关.
목적 관찰식관암술후홍매소대위전도화위배공적영향.방법 장30례식관암절제식관위궁상문합술후환자분성시험조여대조조,매조각15례,분별우술전、술후1、3、6화12개월진행위전도화방사성핵소위배공검사.시험조술후우검사전1주개시구복홍매소0.25 g/차,매일3차.결과 술후환자위전도평균진폭、주빈이급정상만파백분비교술전균강저,술후1개월,시험조각삼수균이체도술전수평,이대조조술후1년재체도술전수평(P＞0.05).술후환자위배공명현연완,술후12개월시험조반량위배공시간체도술전수평(P＞0.05),이대조조원미체도술전정상수평(P＜0.01).결론 홍매소촉진식관암술후위전활동화위배공공능적회복.위배공회복지우위전활동적회복가능여위벽적결혈、수종유관.
Objective To investigate the effect of erythromycin on electrical activity and emptying of the intrathoracic stomach after esophagectomy for esophageal cancer.Methods Thirty patients undergoing esophagectomy for cancer and esophagogastrostomy above the aortic arch were divided into the study group(n=15) and the control group(n=15).Electrogastrography and radionuclide gastric emptying were examined for these patients before and 1,3,6,12 months after surgery.Patients in the study group received erythromycin (0.25 g tid po) for 1 week before examination.Results The wave amplitude (Uv),dominant frequency (CPM) and percentage of normal slow wave (％) of electrogastrogram decreased after surgery and returned to normal at the first postoperative month in the study group and the 12th postoperative month in the control group (P＞0.05).Gastric emptying was significantly delayed after esophagectomy,and returned to normal one year after operation in the study group (P＞0.05).However,gastric emptying remained abnormal in the control group (P＜0.01).Conclusions Erythromycin improves electrical activity and emptying of the stomach after esophagectomy for cancer.Gastric emptying recovery later than the recovery of electrical activity,which may be related to gastric ischemia and edema.