中国医师杂志
中國醫師雜誌
중국의사잡지
JOURNAL OF CHINESE PHYSICIAN
2014年
9期
1196-1199
,共4页
肝炎,乙型/并发症%肝功能衰竭/病因学%肝功能衰竭,急性/并发症%肝功能衰竭/并发症%慢性病%肝肾综合征/病因学%危险因素
肝炎,乙型/併髮癥%肝功能衰竭/病因學%肝功能衰竭,急性/併髮癥%肝功能衰竭/併髮癥%慢性病%肝腎綜閤徵/病因學%危險因素
간염,을형/병발증%간공능쇠갈/병인학%간공능쇠갈,급성/병발증%간공능쇠갈/병발증%만성병%간신종합정/병인학%위험인소
Hepatitis B/complications%Liver failure/etiology%Liver failure,acute/complications%Liver failure/complications%Chronic disease%Hepatorenal syndrome/etiology%Risk factors
目的 探讨分析慢加急性乙型肝炎肝衰竭并发肝肾综合征(HRS)的影响因素.方法 选取2009年1月至2013年12月本院收治的60例慢加急性乙型肝炎肝衰竭患者为研究对象,通过单因素和多因素回归分析患者的基础临床资料、并发症发生情况及基线时临床检测指标,筛选慢加急性乙型肝炎肝衰竭患者肝肾综合征发生的独立危险因素.结果 60例慢加急性乙型肝炎肝衰竭患者发生HRS 17例,发病率为28.3％;多因素Logistic回归分析结果显示血清白蛋白、血钠、肝功能分级(Child-Pugh评分)、晚期肝病模型(MELD)评分、原发性细菌性腹膜炎、上消化道出血、腹水、肝性脑病是慢加急性乙型肝炎肝衰竭患者发生肝肾综合征的危险因素(P＜0.05).结论 慢加急性乙型肝炎肝衰竭患者发生肝肾综合征的患病率较高,动态监测各种敏感指标并及时采取相应的预防及治疗措施,对改善患者预后具有十分重要的意义.
目的 探討分析慢加急性乙型肝炎肝衰竭併髮肝腎綜閤徵(HRS)的影響因素.方法 選取2009年1月至2013年12月本院收治的60例慢加急性乙型肝炎肝衰竭患者為研究對象,通過單因素和多因素迴歸分析患者的基礎臨床資料、併髮癥髮生情況及基線時臨床檢測指標,篩選慢加急性乙型肝炎肝衰竭患者肝腎綜閤徵髮生的獨立危險因素.結果 60例慢加急性乙型肝炎肝衰竭患者髮生HRS 17例,髮病率為28.3％;多因素Logistic迴歸分析結果顯示血清白蛋白、血鈉、肝功能分級(Child-Pugh評分)、晚期肝病模型(MELD)評分、原髮性細菌性腹膜炎、上消化道齣血、腹水、肝性腦病是慢加急性乙型肝炎肝衰竭患者髮生肝腎綜閤徵的危險因素(P＜0.05).結論 慢加急性乙型肝炎肝衰竭患者髮生肝腎綜閤徵的患病率較高,動態鑑測各種敏感指標併及時採取相應的預防及治療措施,對改善患者預後具有十分重要的意義.
목적 탐토분석만가급성을형간염간쇠갈병발간신종합정(HRS)적영향인소.방법 선취2009년1월지2013년12월본원수치적60례만가급성을형간염간쇠갈환자위연구대상,통과단인소화다인소회귀분석환자적기출림상자료、병발증발생정황급기선시림상검측지표,사선만가급성을형간염간쇠갈환자간신종합정발생적독립위험인소.결과 60례만가급성을형간염간쇠갈환자발생HRS 17례,발병솔위28.3％;다인소Logistic회귀분석결과현시혈청백단백、혈납、간공능분급(Child-Pugh평분)、만기간병모형(MELD)평분、원발성세균성복막염、상소화도출혈、복수、간성뇌병시만가급성을형간염간쇠갈환자발생간신종합정적위험인소(P＜0.05).결론 만가급성을형간염간쇠갈환자발생간신종합정적환병솔교고,동태감측각충민감지표병급시채취상응적예방급치료조시,대개선환자예후구유십분중요적의의.
Objective To investigate and analyze the risk factors of the occurrence of hepato renal syndrome (Hepatorenal syndrome,HRS) for patients with acute on chronic hepatitis B liver failure.Methods Sixty cases of patients with acute on chronic hepatitis B liver failure from January 2009 to December 2013 in our hospital were selected as the research objects.The single factor and multi-factor regression analyses were in patients with the basic clinical data,and the complications and the baseline clinical testing index of patients.The independent risk factors of the occurrence of HRS for patients with acute on chronic hepatitis B liver failure were screened.Results The cases of the occurrence of HRS for patients with acute on chronic hepatitis B liver failure was 17 among 60 cases with a incidence of 28.3 ％ ; The results of multivariable logistic regression analysis showed that serum albumin,serum sodium,liver function grade (Child-Pugh score),model for end-stage liver disease (MELD) index,primary bacterial peritonitis,upper gastrointestinal hemorrhage,ascites,and hepatic encephalopathy were the risk factors of the occurrence of HRS for patients with acute on chronic hepatitis B liver failure (P ＜ 0.05).Conclusions The occurrence of HRS for patients with acute on chronic hepatitis B liver failure is higher.The various sensitive indicators should be monitored dynanically,and the relevant prevention and treatment measures should be taken in time.It has a significantly scientific merit to improve the prognosis of patients.
