中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2011年
8期
841-843
,共3页
于鹏%宫凤玲%李文青%梁永平%尚瑞兴%李琳梅%孟强
于鵬%宮鳳玲%李文青%樑永平%尚瑞興%李琳梅%孟彊
우붕%궁봉령%리문청%량영평%상서흥%리림매%맹강
甲状腺癌%放射性核素%99Tcm
甲狀腺癌%放射性覈素%99Tcm
갑상선암%방사성핵소%99Tcm
Thyroid cancer%Radionuclide%99Tcm
目的 探讨99Tcm-MIBI肿瘤阳性显像在诊断甲状腺癌中的应用价值.方法 临床怀疑为甲状腺癌患者54例,分别用SPECT进行99TcmO4-甲状腺静态显像和99Tcm-MIBI肿瘤阳性显像,将显像结果与手术病理结果进行对照.结果 54例患者中,病理结果显示共有甲状腺结节54个,均为单发结节,其中恶性甲状腺结节25个;99TcmO4-甲状腺静态显像共发现甲状腺结节52个,其中热结节2个,温结节4个,凉结节10个,冷结节36个;2例患者显像结果为阴性.25个恶性甲状腺结节中,发现16个有明显的99Tcm-MIBI摄取,均为冷结节;29个良性甲状腺结节中,发现15个有明显的99Tcm-MIBI摄取,其中温结节1个,凉结节2个,冷结节12个.99TcmO4-和99Tcm-MIBI联合核素显像诊断多发性甲状腺结节伴甲状腺癌的灵敏度为64.00%(16/25),特异度为48.28%(14/29).甲状腺良、恶性结节的99Tcm-MIBI肿瘤显像阳性率差异无统计学意义(χ2=0.83,P＞0.05).结论 99Tcm-MIBI肿瘤阳性显像对甲状腺癌的诊断不具有特异性,其l临床应用价值有限.
目的 探討99Tcm-MIBI腫瘤暘性顯像在診斷甲狀腺癌中的應用價值.方法 臨床懷疑為甲狀腺癌患者54例,分彆用SPECT進行99TcmO4-甲狀腺靜態顯像和99Tcm-MIBI腫瘤暘性顯像,將顯像結果與手術病理結果進行對照.結果 54例患者中,病理結果顯示共有甲狀腺結節54箇,均為單髮結節,其中噁性甲狀腺結節25箇;99TcmO4-甲狀腺靜態顯像共髮現甲狀腺結節52箇,其中熱結節2箇,溫結節4箇,涼結節10箇,冷結節36箇;2例患者顯像結果為陰性.25箇噁性甲狀腺結節中,髮現16箇有明顯的99Tcm-MIBI攝取,均為冷結節;29箇良性甲狀腺結節中,髮現15箇有明顯的99Tcm-MIBI攝取,其中溫結節1箇,涼結節2箇,冷結節12箇.99TcmO4-和99Tcm-MIBI聯閤覈素顯像診斷多髮性甲狀腺結節伴甲狀腺癌的靈敏度為64.00%(16/25),特異度為48.28%(14/29).甲狀腺良、噁性結節的99Tcm-MIBI腫瘤顯像暘性率差異無統計學意義(χ2=0.83,P＞0.05).結論 99Tcm-MIBI腫瘤暘性顯像對甲狀腺癌的診斷不具有特異性,其l臨床應用價值有限.
목적 탐토99Tcm-MIBI종류양성현상재진단갑상선암중적응용개치.방법 림상부의위갑상선암환자54례,분별용SPECT진행99TcmO4-갑상선정태현상화99Tcm-MIBI종류양성현상,장현상결과여수술병리결과진행대조.결과 54례환자중,병리결과현시공유갑상선결절54개,균위단발결절,기중악성갑상선결절25개;99TcmO4-갑상선정태현상공발현갑상선결절52개,기중열결절2개,온결절4개,량결절10개,랭결절36개;2례환자현상결과위음성.25개악성갑상선결절중,발현16개유명현적99Tcm-MIBI섭취,균위랭결절;29개량성갑상선결절중,발현15개유명현적99Tcm-MIBI섭취,기중온결절1개,량결절2개,랭결절12개.99TcmO4-화99Tcm-MIBI연합핵소현상진단다발성갑상선결절반갑상선암적령민도위64.00%(16/25),특이도위48.28%(14/29).갑상선량、악성결절적99Tcm-MIBI종류현상양성솔차이무통계학의의(χ2=0.83,P＞0.05).결론 99Tcm-MIBI종류양성현상대갑상선암적진단불구유특이성,기l림상응용개치유한.
Objective To evaluate the value of positive 99Tcm-MIBI tumor imaging for thyroid cancer diagnosis. Methods Fifty four suspected thyroid cancer patients underwent 99Tcm-O4 and 99Tcm-MIBI combined imaging procedure. The imaging data were confirmed by pathological findings. Results All the 54 cases had single throid nodules, and 25 of which were pathologically malignant. Fifty two cases of nodules were detected by the 99Tcm O4 thyroid static imaging, including 2 hot nodules,4 warm nodules, 10 cool nodules and 36 cold nodules;2 cases were negative by the imaging. Of the 25 malignant thyroid nodules, 16 nodules were visible by 99Tcm-MIBI uptake and were cold nodules;29 exhibited benign thyroid nodules,of which 15 could be seen by 99Tcm-MIBI uptake,including 1 warm nodules,2 cool nodules and 12 cold nodules. The sensitivity, specificity of the combined imaging of 99Tcm O4 and 99Tcm-MIBI were 64. 00% ( 16/25 ) and 48. 28% (14/29). No significant difference was found for the positivity between benign nodules and malignancy nodules by 99Tcm-MIBI tumor imaging ( χ2 = 0. 83, P ＞ 0. 05 ). Conclusion 99Tcm-MIBI tumor imaging is not specific for the diagnosis of thyroid malignancy.
