CAJ | 학술논문

目的了解综合性重症监护病房(ICU)获得性感染的流行病学及细菌耐药性情况,为临床治疗提供依据.方法对我院2010年1月1日至2011年12月31日ICU所有分离的细菌菌株、真菌菌株的耐药性进行回顾性调查.结果医院获得性感染中仍以G-菌为主,占73.3％；其次为G+菌17.9％,真菌8.7％.在细菌感染中,G-菌占80.3％,G+菌占19.7％.G-菌仍以铜绿假单胞菌为主,占21.7％.G+菌以金黄色葡萄球菌为主,占31.4％.耐药性方面,细菌耐药性严重,真菌耐药性较轻.结论细菌对常用抗生素的耐药严重,且呈多重耐药.应严格掌握抗生素使用原则,根据药敏试验结果选用抗生素.
목적 료해종합성중증감호병방(ICU)획득성감염적류행병학급세균내약성정황,위림상치료제공의거.방법 대아원2010년1월1일지2011년12월31일ICU소유분리적세균균주、진균균주적내약성진행회고성조사.결과 의원획득성감염중잉이G-균위주,점73.3％；기차위G+균17.9％,진균8.7％.재세균감염중,G-균점80.3％,G+균점19.7％.G-균잉이동록가단포균위주,점21.7％.G+균이금황색포도구균위주,점31.4％.내약성방면,세균내약성엄중,진균내약성교경.결론 세균대상용항생소적내약엄중,차정다중내약.응엄격장악항생소사용원칙,근거약민시험결과선용항생소.
Objective To review the prevalence of nosocomial infection and the change of drug resistance in a comprehensive intensive care unit (ICU) and to provide theoretical basis for clinical prevention and treatment.Methods The strains of bacteria and fungi were isolated from ICU and their drug resistance was retrospectively analyzed from Jan.1st,2010 to Dec.31th,2011.Results The main pathogen of nosocomial infection were Gram-negative bacteria ( 73.3％ ),Gram-positive bacteria ( 17.9％ ) and fungi ( 8.7％ ).In bacterial infection,Gram-negative and G-positive bacteria accounted for 80.3％ and 19.7％ respectively.In Gram-negative bacteria,pseudomonas aeruginosa was the major type (21.7％).In Gram-positive bacteria,staphylococcus aureus (31.4％) was most prominent.Drug resistance of bacteria was severe,while that of fungi was mild.Conclusion Bacteria has severe drug resistance and exhibits multi-drug resistance for commonly used antibiotics.The principle of antibiotics application should be mastered and antibiotics should be chosen according to drug-sensitivity tests.