中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2013年
2期
179-182
,共4页
胰腺癌%高强度聚焦超声%疼痛
胰腺癌%高彊度聚焦超聲%疼痛
이선암%고강도취초초성%동통
Pancreatic carcinoma%High intensity focused ultrasound%Pain
目的 分析高强度聚焦超声(HIFU)消融对中、晚期胰腺癌止痛效果的影响因素和临床特征.方法 胰腺癌患者71例,经HIFU治疗后,根据对疼痛疗效的相关影响因素进行分组并行单因素相关性分析.通过对HIFU消融治疗后疼痛的效果评分,分析各因素与HIFU止痛效果之间的关系.结果 疼痛评分降低≥50％的中晚期胰腺癌患者好发于＜60岁,体质量指数＜22 kg/m2,并且位于胰腺头颈部的肿瘤、肿瘤2 ～5 cm大小、HIFU治疗的平均功率＞400W、肿瘤组织学分型的导管腺癌均与HIFU消融疼痛缓解程度有关,差异有统计学意义(P均＜0.05).且HIFU消融后并发症少.结论 对中、晚期胰腺癌不同因素与止痛效果的关系分析,可进一步指导临床预测HIFU的治疗效果.
目的 分析高彊度聚焦超聲(HIFU)消融對中、晚期胰腺癌止痛效果的影響因素和臨床特徵.方法 胰腺癌患者71例,經HIFU治療後,根據對疼痛療效的相關影響因素進行分組併行單因素相關性分析.通過對HIFU消融治療後疼痛的效果評分,分析各因素與HIFU止痛效果之間的關繫.結果 疼痛評分降低≥50％的中晚期胰腺癌患者好髮于＜60歲,體質量指數＜22 kg/m2,併且位于胰腺頭頸部的腫瘤、腫瘤2 ～5 cm大小、HIFU治療的平均功率＞400W、腫瘤組織學分型的導管腺癌均與HIFU消融疼痛緩解程度有關,差異有統計學意義(P均＜0.05).且HIFU消融後併髮癥少.結論 對中、晚期胰腺癌不同因素與止痛效果的關繫分析,可進一步指導臨床預測HIFU的治療效果.
목적 분석고강도취초초성(HIFU)소융대중、만기이선암지통효과적영향인소화림상특정.방법 이선암환자71례,경HIFU치료후,근거대동통료효적상관영향인소진행분조병행단인소상관성분석.통과대HIFU소융치료후동통적효과평분,분석각인소여HIFU지통효과지간적관계.결과 동통평분강저≥50％적중만기이선암환자호발우＜60세,체질량지수＜22 kg/m2,병차위우이선두경부적종류、종류2 ～5 cm대소、HIFU치료적평균공솔＞400W、종류조직학분형적도관선암균여HIFU소융동통완해정도유관,차이유통계학의의(P균＜0.05).차HIFU소융후병발증소.결론 대중、만기이선암불동인소여지통효과적관계분석,가진일보지도림상예측HIFU적치료효과.
Objective To study the influencing factors and clinical characteristic of High Intensity Focused Ultrasound(HIFU) abhtion analgesic in middle-late stage pancreatic carcinoma.Methods Seventyone cases pancreatic cancer patients underwent HIFU treatment were grouped according to the pain efficacy of related influencing factors and the data was analyzed by single factor correlation analysis.The relationship between influencing factors and analgesic effect were analyzed through the pain outcome score.Results Pain score decreased ≥50％ in advanced pancreatic cancer patients occurred in ＜60 years old,Body mass index (BMI) ＜ 22 kg/m2,tumor location in the pancreatic head and neck,tumor size of 2-5 cm,and the average power of HIFU treatment ＞ 400 W,Ductal adenocarcinoma of the tumor histological type were related to the degree of pain rehef,and the difference was statistically significant (P ＜ 0.05).And fewer complications occurred after HIFU ablation.Conclusion Analysis of the relationship between the different factors and the analgesic effect in advanced pancreatic carcinoma can be used to predict the efficacy of HIFU treatment.
