中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2013年
7期
718-720
,共3页
B型钠尿肽%急性生理和慢性健康状况评分系统Ⅱ评分%危重病%预后
B型鈉尿肽%急性生理和慢性健康狀況評分繫統Ⅱ評分%危重病%預後
B형납뇨태%급성생리화만성건강상황평분계통Ⅱ평분%위중병%예후
B-type natriuretic peptide%APACHE Ⅱ score%Critical Care%Prognosis
目的 探讨B型钠尿肽(BNP)与非心脏病ICU患者严重程度及近期预后的相关性.方法 对2010年3月至2012年3月我院ICU病房的60例危重症患者,分别在入院时、24 h进行急性生理和慢性健康状况评分系统Ⅱ(APACHEⅡ)评分及测定血清BNP浓度,分析两者与危重症患者的病死率、住院时间、机械通气的时间等主要预后指标的关系.结果 60例患者存活42例,死亡18例,病死率为30％,其中死亡组APACHEⅡ评分(26.46±11.61)分和血清BNP浓度(2154.26±1126.49) ng/L,均明显高于存活组(13.45±4.20)分和(1058.16±857.83) ng/L(t值分别为6.4055和4.1190,P均＜0.001),APACHEⅡ评分、机械通气的时间及病死率随BNP浓度升高而升高(F值分别为49.089、22.754、36.398,P均＜0.001).结论 BNP和APACHEⅡ评分的升高对危重症患者的存活、机械通气时间、住院时间等主要预后指标的预测有重要意义.
目的 探討B型鈉尿肽(BNP)與非心髒病ICU患者嚴重程度及近期預後的相關性.方法 對2010年3月至2012年3月我院ICU病房的60例危重癥患者,分彆在入院時、24 h進行急性生理和慢性健康狀況評分繫統Ⅱ(APACHEⅡ)評分及測定血清BNP濃度,分析兩者與危重癥患者的病死率、住院時間、機械通氣的時間等主要預後指標的關繫.結果 60例患者存活42例,死亡18例,病死率為30％,其中死亡組APACHEⅡ評分(26.46±11.61)分和血清BNP濃度(2154.26±1126.49) ng/L,均明顯高于存活組(13.45±4.20)分和(1058.16±857.83) ng/L(t值分彆為6.4055和4.1190,P均＜0.001),APACHEⅡ評分、機械通氣的時間及病死率隨BNP濃度升高而升高(F值分彆為49.089、22.754、36.398,P均＜0.001).結論 BNP和APACHEⅡ評分的升高對危重癥患者的存活、機械通氣時間、住院時間等主要預後指標的預測有重要意義.
목적 탐토B형납뇨태(BNP)여비심장병ICU환자엄중정도급근기예후적상관성.방법 대2010년3월지2012년3월아원ICU병방적60례위중증환자,분별재입원시、24 h진행급성생리화만성건강상황평분계통Ⅱ(APACHEⅡ)평분급측정혈청BNP농도,분석량자여위중증환자적병사솔、주원시간、궤계통기적시간등주요예후지표적관계.결과 60례환자존활42례,사망18례,병사솔위30％,기중사망조APACHEⅡ평분(26.46±11.61)분화혈청BNP농도(2154.26±1126.49) ng/L,균명현고우존활조(13.45±4.20)분화(1058.16±857.83) ng/L(t치분별위6.4055화4.1190,P균＜0.001),APACHEⅡ평분、궤계통기적시간급병사솔수BNP농도승고이승고(F치분별위49.089、22.754、36.398,P균＜0.001).결론 BNP화APACHEⅡ평분적승고대위중증환자적존활、궤계통기시간、주원시간등주요예후지표적예측유중요의의.
Objective To investigate the correlations of short-term prognosis and B-type natriuretic peptide(BNP) of no heart disease patients in ICU.Methods Sixty patients of critically ill in our ICU ward from March 2010 to March 2012 were taken scores of acute physiology and chronic health Ⅱ scoring system (APACHE Ⅱ score) and determination serum BNP level in 24 hours of admission and analysis mortality in hospital time,mechanical ventilation time and other major prognostic indicators.Results Forty-two cases were living,18 cases were dead in the 60 cases (mortality rate 30％).APACHE Ⅱ score (26.46 ± 11.6) and serum BNP concentrations(2154.26 ± 1126.49) ng/L were significantly higher in death cases than in living cases (13.45 ± 4.20) vs.(1058.16 ± 857.83) ng/L (t =6.4055,4.1190,P ＜ 0.001),mechanical ventilation time mortality rate both also increase with BNP levels (F =49.089,22.754,36.398 respectively,P ＜ 0.001).Conclusion BNP level and APACHE Ⅱ score rise of survival of critically ill patients have important prognostic significance with duration of mechanical ventilation,length of hospital stay prognostic indicators forecast.
