中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2013年
8期
790-792
,共3页
何艳舫%刘萍%韩素新%左振伟
何豔舫%劉萍%韓素新%左振偉
하염방%류평%한소신%좌진위
多囊卵巢综合征%重组人生长激素%妊娠
多囊卵巢綜閤徵%重組人生長激素%妊娠
다낭란소종합정%중조인생장격소%임신
Polycysticovary syndrome%Growth hormone%Pregnancy
目的 探讨重组人生长激素(rhGH)对提高多囊卵巢综合征(PCOS)患者妊娠率的作用.方法 选择2012年2-8月来我院门诊就诊的82例PCOS患者为研究对象,所有研究对象经纠正异常激素水平后随机分为两组,rhGH组(41例)在促排卵周期加用rhGH,并指导受孕.对照组(41例)直接促排卵治疗并指导受孕.对两组的排卵率、妊娠率及子宫内膜评分进行比较.结果 rhGH组的排卵率为90.2％ (37/41),对照组为68.2％ (28/41),差异有统计学意义(x2=3.459,P=0.036).rhGH组的临床妊娠率为32.7％ (12/37),对照组为25.0％(7/28),差异有统计学意义(x2 =4.319,P=0.032).rhGH 组子宫内膜评分为(14.96±2.18)分,对照组为(12.77±2.60)分,组间比较差异有统计学意义(t=-3.356,P=0.032).结论 促排卵周期规范地给予rhGH可促进PCOS患者排卵,改善影响妊娠的不良因素,提高妊娠率.
目的 探討重組人生長激素(rhGH)對提高多囊卵巢綜閤徵(PCOS)患者妊娠率的作用.方法 選擇2012年2-8月來我院門診就診的82例PCOS患者為研究對象,所有研究對象經糾正異常激素水平後隨機分為兩組,rhGH組(41例)在促排卵週期加用rhGH,併指導受孕.對照組(41例)直接促排卵治療併指導受孕.對兩組的排卵率、妊娠率及子宮內膜評分進行比較.結果 rhGH組的排卵率為90.2％ (37/41),對照組為68.2％ (28/41),差異有統計學意義(x2=3.459,P=0.036).rhGH組的臨床妊娠率為32.7％ (12/37),對照組為25.0％(7/28),差異有統計學意義(x2 =4.319,P=0.032).rhGH 組子宮內膜評分為(14.96±2.18)分,對照組為(12.77±2.60)分,組間比較差異有統計學意義(t=-3.356,P=0.032).結論 促排卵週期規範地給予rhGH可促進PCOS患者排卵,改善影響妊娠的不良因素,提高妊娠率.
목적 탐토중조인생장격소(rhGH)대제고다낭란소종합정(PCOS)환자임신솔적작용.방법 선택2012년2-8월래아원문진취진적82례PCOS환자위연구대상,소유연구대상경규정이상격소수평후수궤분위량조,rhGH조(41례)재촉배란주기가용rhGH,병지도수잉.대조조(41례)직접촉배란치료병지도수잉.대량조적배란솔、임신솔급자궁내막평분진행비교.결과 rhGH조적배란솔위90.2％ (37/41),대조조위68.2％ (28/41),차이유통계학의의(x2=3.459,P=0.036).rhGH조적림상임신솔위32.7％ (12/37),대조조위25.0％(7/28),차이유통계학의의(x2 =4.319,P=0.032).rhGH 조자궁내막평분위(14.96±2.18)분,대조조위(12.77±2.60)분,조간비교차이유통계학의의(t=-3.356,P=0.032).결론 촉배란주기규범지급여rhGH가촉진PCOS환자배란,개선영향임신적불량인소,제고임신솔.
Objective To investigate the effect of recombinant human growth hormone (rhGH) action on pregnancy rate of polycystic ovarian syndrome(PCOS).Methods The PCOS who were client in our hospital in February-August,2012 were investigated.The rhGH group (41 cases) were that all patients took rhGH at the same time ovulation.The control group (41 cases) were no medication group.The two groups had sex action after ovulation.Ovulation rate,pregnancy rate and endometrial score of the two groups were compared.Results Ovulation rate of rhGH group was 90.2％ (37/41),the control group was 68.2％ (28/41),the difference was statistically significant (x2 =3.459,P =0.036).Clinical pregnancy rate of RhGH group was 32.7％ (12/37),the control group was 25.0％ (7/28).The difference was statistics significance (x2 =4.319,P =0.032).Endometrial score of rhGH group was (14.96 ± 2.18),the control group was (12.77 ± 2.60) points,the difference between groups was statistically significant (t =-3.356,P =0.032).Conclusion Giving rhGH ovulation cycle specification can promote ovulation PCOS patients and improve the adverse factors affecting pregnancy,improving the pregnancy rate.
