中华传染病杂志
中華傳染病雜誌
중화전염병잡지
CHINESE JOURNAL OF INFECTIOUS DISEASES
2009年
10期
599-602
,共4页
王建%杨湛%尹炽标%洪文昕%胡凤玉%雷春亮%蔡卫平%魏绍静%张复春
王建%楊湛%尹熾標%洪文昕%鬍鳳玉%雷春亮%蔡衛平%魏紹靜%張複春
왕건%양담%윤치표%홍문흔%호봉옥%뢰춘량%채위평%위소정%장복춘
流感%人%流感病毒A型%H1N1亚型%聚合酶链反应
流感%人%流感病毒A型%H1N1亞型%聚閤酶鏈反應
류감%인%류감병독A형%H1N1아형%취합매련반응
Influenza%human%Influenza A virus%H1N1 subtype%Polymerase chain reaction
目的 了解2009年广东省首例输入性甲型H1N1流行性感冒(流感)病例的流行病学、临床、病原学特点及预后转归.方法 对该例成年男性患者流行病学及临床资料进行回顾性分析,并采用实时荧光PCR法检测甲型H1N1流感病毒核酸.结果 该患者赴加拿大、美国自助旅游3周,2009年5月14日发病,次日回国入境检疫时有发热,即转送广州市第八人民医院隔离治疗.其临床表现以咽痛、干咳、鼻塞起病,后出现发热、全身肌肉酸痛、乏力、纳差等流感症状,无肺炎等并发症.WBC总数在发病初期升高,后期降低.咽拭子检测甲型H1N1流感病毒核酸阳性,病毒分离后测序结果显示与美国分离株高度相似.患者经抗病毒及对症支持治疗后痊愈出院.结论 该患者临床表现典型,确诊为广东省首例输入性甲型H1N1流感.
目的 瞭解2009年廣東省首例輸入性甲型H1N1流行性感冒(流感)病例的流行病學、臨床、病原學特點及預後轉歸.方法 對該例成年男性患者流行病學及臨床資料進行迴顧性分析,併採用實時熒光PCR法檢測甲型H1N1流感病毒覈痠.結果 該患者赴加拿大、美國自助旅遊3週,2009年5月14日髮病,次日迴國入境檢疫時有髮熱,即轉送廣州市第八人民醫院隔離治療.其臨床錶現以嚥痛、榦咳、鼻塞起病,後齣現髮熱、全身肌肉痠痛、乏力、納差等流感癥狀,無肺炎等併髮癥.WBC總數在髮病初期升高,後期降低.嚥拭子檢測甲型H1N1流感病毒覈痠暘性,病毒分離後測序結果顯示與美國分離株高度相似.患者經抗病毒及對癥支持治療後痊愈齣院.結論 該患者臨床錶現典型,確診為廣東省首例輸入性甲型H1N1流感.
목적 료해2009년광동성수례수입성갑형H1N1류행성감모(류감)병례적류행병학、림상、병원학특점급예후전귀.방법 대해례성년남성환자류행병학급림상자료진행회고성분석,병채용실시형광PCR법검측갑형H1N1류감병독핵산.결과 해환자부가나대、미국자조여유3주,2009년5월14일발병,차일회국입경검역시유발열,즉전송엄주시제팔인민의원격리치료.기림상표현이인통、간해、비새기병,후출현발열、전신기육산통、핍력、납차등류감증상,무폐염등병발증.WBC총수재발병초기승고,후기강저.인식자검측갑형H1N1류감병독핵산양성,병독분리후측서결과현시여미국분리주고도상사.환자경항병독급대증지지치료후전유출원.결론 해환자림상표현전형,학진위광동성수례수입성갑형H1N1류감.
Objective To investigate the epidemiological,clinical and pathogenic characteristics and prognosis of the first imported case of influenza A/H1N1 in Guangdong Province in 2009.Methods Epidemiological and clinical data of this male adult patient were analyzed retrospectively.Influenza A/H1N1 RNA was detected using real-time fluorescent polymerase chain reaction.Results This patient had traveled to Canada and America for 3 weeks.And he had became ill at May 14th and found febrile during entry quarantine on next day when he returned China.He was been isolated and treated in Guangzhou No.8 people's Hospital after that immediately.The first presenting symptoms were angina,cough and nasal obstruction.Then he had fever,muscle pains,asthenia on next day.But he had no complications including pneumonia.The laboratory tests showed leukocytosis in the early stage of the disease and leucopenia in later stage.Influenza A/H1N1 RNA was detected positive after the onset.The virus isolate from the patient was sequenced,it was highly homology to isolated strain in the United States.The patient recovered with antivirus and symptomatic supportive treatment.Conclusions This imported case of influenza A(H1N1)is reported for the first time in Guangdong.The clinical feature of the case is typical.
