CAJ | 학술논문

目的了解AIDS患者机会性感染的常见病原体、感染部位、临床特征,为制定科学诊疗方案提供依据.方法对AIDS定点医院6年收治的603例AIDS患者的临床资料进行回顾性分析.结果 603例AIDS患者中,327例(54.2％)合并耶氏肺孢子菌感染,251例(41.6％)合并真菌感染,210例(34.8％)合并分枝杆菌感染.367例(60.9％)患者为单种病原体感染,236例(39.1％)患者同时合并2种及以上病原体感染.390例(64.7％)患者单一部位感染,其中呼吸道最常见(271例,69.5％)；213例(35.3％)患者存在2个及以上部位的感染,其中最多见为口咽十呼吸道同时感染(111例,52.1％).结论 AIDS患者机会性感染多为多部位、多病原体重叠感染,早期发现、及时有效治疗可以治愈大部分机会性感染,延长患者生命,提高患者生活质量.
목적 료해AIDS환자궤회성감염적상견병원체、감염부위、림상특정,위제정과학진료방안제공의거.방법 대AIDS정점의원6년수치적603례AIDS환자적림상자료진행회고성분석.결과 603례AIDS환자중,327례(54.2％)합병야씨폐포자균감염,251례(41.6％)합병진균감염,210례(34.8％)합병분지간균감염.367례(60.9％)환자위단충병원체감염,236례(39.1％)환자동시합병2충급이상병원체감염.390례(64.7％)환자단일부위감염,기중호흡도최상견(271례,69.5％)；213례(35.3％)환자존재2개급이상부위적감염,기중최다견위구인십호흡도동시감염(111례,52.1％).결론 AIDS환자궤회성감염다위다부위、다병원체중첩감염,조기발현、급시유효치료가이치유대부분궤회성감염,연장환자생명,제고환자생활질량.
Objective To investigate the characteristics of opportunistic infections in acquired immunodeficiency syndrome (AIDS) patients.Methods A comprehensive retrospective chart review study was conducted of 603 AIDS patients with different opportunistic infections in a special hospital authorized for AIDS patients.Results In all 603 patients,327 cases (54.2％) were infected with Pneumocystisjiroveci,251 cases (41.6％) were infected with fungus and 210 cases (34.8％) were infected with mycobacterium.Totally 367 cases (60.9％) had only one pathogen and 236 cases (39.1％) were co-infected with more than one pathogen.A total of 390 cases (64.7％) had a single site of infection with the respiratory tract being most frequently involved (271 cases,69.5％),and 213 cases (35.3％) had more than one infected site.The most common coinfected sites were oropharynx and respiratory tract (111 cases,52.1％).Conclusions AIDS patients are usually coinfected with multiple pathogenic organisms and multi-systems involved.Most of the opportunistic infections can be cured by timely diagnosis and effective treatment to prolong life and improve the quality of life of AIDS patients.