CAJ | 학술논문

目的探讨大片形吸虫感染的流行病学特点、临床表现、诊断和治疗方法,为大片形吸虫病的诊治提供参考.方法回顾性分析4例确诊为大片形吸虫病患者的流行病学资料、临床表现、实验室检查结果、影像学表现、诊断和治疗转归情况.结果 4例大片形吸虫病患者均为云南省大理州宾川县农民,均表现为发热、肝区疼痛和叩痛、肝脏肿大、嗜酸粒细胞增多、球蛋白升高、血WBC和中性粒细胞升高、不同程度的贫血,肝脏CT扫描均提示肝实质内散在多发低密度影,粪便检出大片形吸虫卵,ELISA检测大片形吸虫抗体均阳性,三氯苯达唑治疗效果显著.结论人体感染大片形吸虫少见,无特异性临床表现,三氯苯达唑是治疗的首选药物.
목적 탐토대편형흡충감염적류행병학특점、림상표현、진단화치료방법,위대편형흡충병적진치제공삼고.방법 회고성분석4례학진위대편형흡충병환자적류행병학자료、림상표현、실험실검사결과、영상학표현、진단화치료전귀정황.결과 4례대편형흡충병환자균위운남성대리주빈천현농민,균표현위발열、간구동통화고통、간장종대、기산립세포증다、구단백승고、혈WBC화중성립세포승고、불동정도적빈혈,간장CT소묘균제시간실질내산재다발저밀도영,분편검출대편형흡충란,ELISA검측대편형흡충항체균양성,삼록분체서치료효과현저.결론 인체감염대편형흡충소견,무특이성림상표현,삼록분체서시치료적수선약물.
Objective To explore the epidemiological characteristics,clinical manifestations,diagnosis and treatment of Fasciola gigantica infection,and to provide reference for future diagnosis and treatment.Methods Four cases of confirmed Fasciola gigantica infection were analyzed retrospectively for epidemiological information,clinical manifestations,laboratory results,imaging findings,diagnosis and treatment outcomes.Results Four Fasciola gigantica infection cases were farmers from Binchuan County,Yunnan Province.All presented with fever,hepatalgia,percussion pain,hepatomegaly,eosinophilia,hyperglobulinemia,neutrophilia and anemia.Computed tomography (CT) scans showed multiple low density shadows scattered in the liver parenchyma.Eggs of Fasciola gigantica were detected in feces of the patients,and results of antibody against Fasciola gigantica detected by enzyme-linked immunosorhent assay (ELISA) were positive.Triclabendazole treatment was effective.Conclusion Human Fasciola gigantica infection is rare,without specific clinical manifestations,and triclabendazole is the first choice of treatment.