CAJ | 학술논문

目的应用四维应变(4D strain)技术分析正常人左室17节段收缩期面积应变峰值及达峰时序分布规律,探讨其临床应用价值.方法健康志愿者31例,采集左室实时三维全容积动态图像,应用EchoPAC分析软件测量左室容积及功能参数,以及各节段及整体收缩期面积应变峰值及应变达峰时间,分析面积应变参数在左室各节段的分布规律及节段参数在检查者间、检查者内的差异,以及左室整体面积应变峰值与射血分数的相关性.结果下壁基底段、左室心尖部收缩期面积应变峰值较小；左心室下壁、后室间隔、前室间隔基底段应变达峰时间较早；节段面积应变参数重复性较好；左室整体面积应变峰值与射血分数呈负相关(r=-0.688,P=0.000).结论四维应变技术测量的面积应变参数可用于定量分析左心室心肌收缩模式及左室收缩功能.
목적 응용사유응변(4D strain)기술분석정상인좌실17절단수축기면적응변봉치급체봉시서분포규률,탐토기림상응용개치.방법 건강지원자31례,채집좌실실시삼유전용적동태도상,응용EchoPAC분석연건측량좌실용적급공능삼수,이급각절단급정체수축기면적응변봉치급응변체봉시간,분석면적응변삼수재좌실각절단적분포규률급절단삼수재검사자간、검사자내적차이,이급좌실정체면적응변봉치여사혈분수적상관성.결과 하벽기저단、좌실심첨부수축기면적응변봉치교소；좌심실하벽、후실간격、전실간격기저단응변체봉시간교조；절단면적응변삼수중복성교호；좌실정체면적응변봉치여사혈분수정부상관(r=-0.688,P=0.000).결론 사유응변기술측량적면적응변삼수가용우정량분석좌심실심기수축모식급좌실수축공능.
Objective To evaluate left ventricular (LV) myocardial contraction patterns and function by analyzing the distribution of peak value of segmental area strain and time sequence to the peak value.Methods 31 healthy subjects were involved.Real-time three dimensional full volume images of LV were acquired and analyzed with EchoPAC.LV volume and function parameters,as well as segmental and global systolic area strain and time to peak value were measured.The distribution of peak segmental area strain and time sequence to the peak value,interobserver and intraobserver variability of area strain parameters,as well as the relationship between global area strain and ejection fraction were evaluated.Results The peak segmental area strain was lower in the basic inferior and apical segments,and the peak value was reached earlier in the basic inferior,anteroseptal,and septal segments.Intraobserver and interobserver reliability of area strain parameters were good.Furthermore,a negative correlation was observed between global area strain and ejection fraction (r =-0.688,P =0.000).Conclusions The area strain measured by 4D strain can be used to evaluate the LV myocardial motion pattern and function.